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Found 5,419 Skills
Structure prediction using Boltz-1/Boltz-2, an open biomolecular structure predictor. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For Chai prediction, use chai.
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use proteinmpnn. For solubility optimization, use solublempnn.
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design. For QC thresholds, use protein-qc.
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.
ESM2 protein language model for embeddings and sequence scoring. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai or boltz. For QC thresholds, use protein-qc.
Automatically discover observability and monitoring skills when working with Prometheus, Grafana, distributed tracing, structured logging, metrics, alerting, dashboards, or monitoring. Activates for observability development tasks.
Production-grade mobile app development with Swift (iOS), Kotlin (Android), React Native, and WebView patterns, including UI/UX, navigation, state management, networking, local storage, push notifications, and App Store deployment.
Automatically discover mobile development skills when working with iOS, Android, Swift, SwiftUI, React Native, mobile development, SwiftData, or app development. Activates for mobile development tasks.
Expert patterns for porting desktop games to mobile including touch control schemes (virtual joystick, gesture detection), UI scaling for small screens, performance optimization for mobile GPUs, battery life management, and platform-specific features. Use when creating mobile ports or cross-platform mobile builds. Trigger keywords: TouchScreenButton, virtual_joystick, gesture_detector, InputEventScreenTouch, InputEventScreenDrag, mobile_optimization, battery_saving, adaptive_performance, MOBILE_ENABLED.
Production-grade mobile app development and architecture for iOS (Swift/SwiftUI/UIKit), Android (Kotlin/Jetpack Compose), and cross-platform (React Native, Flutter, Kotlin Multiplatform, WebView). Use for navigation, state, networking, offline storage, auth/passkeys, push, performance, testing, CI/CD, and App Store/Play release readiness.
Docusaurus build health validation and deployment safety for Claude Skills showcase. Pre-commit MDX validation (Liquid syntax, angle brackets, prop mismatches), pre-build link checking, post-build health reports. Activate on 'build errors', 'commit hooks', 'deployment safety', 'site health', 'MDX validation'. NOT for general DevOps (use deployment-engineer), Kubernetes/cloud infrastructure (use kubernetes-architect), runtime monitoring (use observability-engineer), or non-Docusaurus projects.