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Found 242 Skills
Build and interpret polygenic risk scores (PRS) for complex diseases using GWAS summary statistics. Calculates genetic risk profiles, interprets PRS percentiles, and assesses disease predisposition across conditions including type 2 diabetes, coronary artery disease, and Alzheimer's disease. Use when asked to calculate polygenic risk scores, interpret genetic risk for complex diseases, build custom PRS from GWAS data, or answer questions like "What is my genetic predisposition to breast cancer?"
Analyze, draft, and review Survival clauses for General contracts. Use when the user mentions survival clause, surviving provisions, post-termination obligations, or asks to review, redline, or generate this clause type. Returns structured risk assessment, plain-language summary, and suggested alternative language.
Surface, prioritize, and track risky assumptions before investing significant effort. Use when starting a new project, before major feature work, when feeling uncertain about direction, when the user says "I think users want...", "we assume...", "probably...", or before any build decision that hasn't been validated with real users.
US stock market sentiment monitoring and position recommendation system. Evaluates market sentiment by tracking 5 core indicators (NAAIM Exposure Index, Institutional Equity Allocation, Retail Net Buying, S&P 500 Forward P/E Ratio, Hedge Fund Leverage) and outputs sentiment ratings and position recommendations. This skill should be used when the user mentions topics such as US stock sentiment, market overheating, greed/fear indicators, NAAIM, institutional positioning, retail sentiment, P/E valuation bubbles, hedge fund leverage, whether to reduce positions, market risk assessment, position management advice, market top/bottom signals, etc. Even if the user simply asks "Is the US stock market risky right now?" or "Should I reduce my positions?", this skill should be triggered to provide a structured analytical framework.
Identify early warning signals of potential PR crises through pattern recognition, escalation triggers, and risk assessment
Review a contract, agreement, terms-of-service, MSA, NDA, employment agreement, vendor SOW, or any legal document. Flag risks, missing terms, unusual clauses, and points worth negotiating. Use this whenever the user says 'review this contract,' 'look at this agreement,' 'is this contract fair,' 'red flags in this,' 'should I sign,' 'help me negotiate,' 'check this NDA,' or attaches/pastes any contract-like document. Output is a structured markdown review the user can read in 5 minutes before signing or negotiating.
Use when you need to analyze git diffs or pull requests to understand what changed, affected components, and risks
Systematic code maturity assessment using Trail of Bits' 9-category framework. Analyzes codebase for arithmetic safety, auditing practices, access controls, complexity, decentralization, documentation, MEV risks, low-level code, and testing. Produces professional scorecard with evidence-based ratings and actionable recommendations.
Find and compare DeFi yield opportunities across protocols with APY calculations, risk assessment, and optimization recommendations. Use when searching for yield farming opportunities, comparing DeFi protocols, or analyzing APY/APR rates. Trigger with phrases like "find DeFi yields", "compare APY", "best yield farming", "optimize DeFi returns", "stablecoin yields", or "liquidity pool rates".
Predicts future bug hotspots by analyzing code complexity, churn, and historical defect patterns. Warns developers before a bug is even written.
Comprehensive drug-drug interaction (DDI) prediction and risk assessment. Analyzes interaction mechanisms (CYP450, transporters, pharmacodynamic), severity classification, clinical evidence grading, and provides management strategies. Supports single drug pairs, polypharmacy analysis (3+ drugs), and alternative drug recommendations. Use when users ask about drug interactions, medication safety, polypharmacy risks, or need DDI assessment for clinical decision support.
Evaluate and configure SPL token authorities (mint/freeze/close) with risk implications and best practices. Use for audits, rotations, or disclosures.