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Found 352 Skills
Offer a structured but non-clinical space for a PhD student or researcher to check in on their mental and emotional state, especially around imposter syndrome, guilt about rest, chronic over-promising, and burnout signals. Use this skill when the user expresses feelings of inadequacy, constant comparison to peers, fear of disappointing their advisor, guilt about taking time off, or exhaustion that isn't just physical. Trigger on phrases like "I feel behind", "everyone is smarter than me", "I can't rest", "I'm burned out", "imposter syndrome", "I'm not good enough", "I'm afraid of disappointing", "I should be working", or whenever the tone of the user's message suggests emotional strain rather than a technical question. Also trigger gently if these signals appear incidentally in a task-focused conversation.
Test quality review drawing on twelve classic engineering books — with primary focus on xUnit Test Patterns, The Art of Unit Testing, How Google Tests Software, and Working Effectively with Legacy Code — that diagnoses structural problems in an existing test suite: brittleness, mock abuse, coverage illusions, slow execution, poor readability. Triggers when: user asks about test quality, shares test files for review, or expresses frustration: "tests keep breaking whenever I change anything", "our tests take forever", "I can't understand what this test is doing", "tests pass but bugs still reach production", "we have too many mocks". Do NOT trigger for: writing new tests from scratch (use the regular test-writing workflow) or testing framework/syntax questions — this skill reviews an existing suite for structural quality problems, not individual test authoring.
Prioritize drug targets from a ranked gene list (e.g., scRNA-seq DE output) by orchestrating parallel API queries against UniProt, OpenTargets (with integrated DepMap CRISPR essentiality + gnomAD constraint), PubMed, the Human Protein Atlas (HPA), and ChEMBL tool compounds, then re-ranking by a composite score combining protein localization, druggability, disease genetics, tissue specificity (safety), focus-cell-type expression, CRISPR essentiality, LoF safety constraint, and research maturity. Use whenever the user wants to filter, triage, prioritize, or "do due diligence" on a list of candidate genes for drug discovery, especially after a DE / DEG analysis when they say things like "which of these should I follow up on", "filter for druggable targets", "make a target dossier", "rank these for tractability", "annotate these genes for druggability", or "build a target report". Trigger even when the user says just "filter these candidate genes" or hands over a CSV from a DE pipeline.
Migrate to Cloudflare Workers from AWS Lambda, Vercel, Express, and Node.js. Use when porting existing applications to the edge, adapting serverless functions, or resolving Node.js API compatibility issues.
This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and other single-cell modalities. Use this skill for probabilistic modeling, batch correction, dimensionality reduction, differential expression, cell type annotation, multimodal integration, and spatial analysis tasks.
Run nf-core bioinformatics pipelines (rnaseq, sarek, atacseq) on sequencing data. Use when analyzing RNA-seq, WGS/WES, or ATAC-seq data—either local FASTQs or public datasets from GEO/SRA. Triggers on nf-core, Nextflow, FASTQ analysis, variant calling, gene expression, differential expression, GEO reanalysis, GSE/GSM/SRR accessions, or samplesheet creation.
Load this skill immediately when the user expresses any intent. System capabilities (tools/knowledge/scripts) live inside the plugin and are maintained through plugin updates. User data must live at project-level `.claude/pensieve/` and is never overwritten by the plugin. When the user asks to improve Pensieve system behavior (plugin content), you must use the Self-Improve tool (`tools/self-improve/_self-improve.md`).
Generates Bruno collection files (.bru) from Express, Next.js, Fastify, or other API routes. Creates organized collections with environments, authentication, and folder structure for the open-source Bruno API client. Use when users request "generate bruno collection", "bruno api testing", "create bru files", or "bruno import".
Runs packages temporarily, creates isolated shell environments, and evaluates Nix expressions. Use when executing tools without installing, debugging derivations, or working with nixpkgs.
Generates comprehensive API test suites using Jest, Vitest, or Supertest from Express, Next.js, Fastify, or other API routes. Creates integration tests, contract tests, and edge case coverage. Use when users request "generate api tests", "create endpoint tests", "api test suite", or "integration tests for api".
Expert patterns for AnimationTree including StateMachine transitions, BlendSpace2D for directional movement, BlendTree for layered animations, root motion, transition conditions, advance expressions, and state machine sub-states. Use for complex character animation systems with movement blending and state management. Trigger keywords: AnimationTree, AnimationNodeStateMachine, BlendSpace2D, BlendSpace1D, BlendTree, transition_request, blend_position, advance_expression, AnimationNodeAdd2, AnimationNodeBlend2, root_motion.
Create a delightful, unexpected "wow" experience for the user by dynamically discovering and creatively combining other enabled skills. Triggers when the user says "surprise me" or any request expressing a desire for an unexpected creative showcase. Also triggers when the user is bored, wants inspiration, or asks for "something interesting".