adaptyv

Original：🇺🇸 English

Translated

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

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Sourcedavila7/claude-code-templates

Added on2026-02-04

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Adaptyv

Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or web interface and receive experimental results in approximately 21 days.

Quick Start

Authentication Setup

Adaptyv requires API authentication. Set up your credentials:

Contact support@adaptyvbio.com to request API access (platform is in alpha/beta)
Receive your API access token
Set environment variable:

bash

export ADAPTYV_API_KEY="your_api_key_here"

Or create a

.env

file:

ADAPTYV_API_KEY=your_api_key_here

Installation

Install the required package using uv:

bash

uv pip install requests python-dotenv

Basic Usage

Submit protein sequences for testing:

python

import os
import requests
from dotenv import load_dotenv

load_dotenv()

api_key = os.getenv("ADAPTYV_API_KEY")
base_url = "https://kq5jp7qj7wdqklhsxmovkzn4l40obksv.lambda-url.eu-central-1.on.aws"

headers = {
    "Authorization": f"Bearer {api_key}",
    "Content-Type": "application/json"
}

# Submit experiment
response = requests.post(
    f"{base_url}/experiments",
    headers=headers,
    json={
        "sequences": ">protein1\nMKVLWALLGLLGAA...",
        "experiment_type": "binding",
        "webhook_url": "https://your-webhook.com/callback"
    }
)

experiment_id = response.json()["experiment_id"]

Available Experiment Types

Adaptyv supports multiple assay types:

Binding assays - Test protein-target interactions using biolayer interferometry
Expression testing - Measure protein expression levels
Thermostability - Characterize protein thermal stability
Enzyme activity - Assess enzymatic function

See

reference/experiments.md

for detailed information on each experiment type and workflows.

Protein Sequence Optimization

Before submitting sequences, optimize them for better expression and stability:

Common issues to address:

Unpaired cysteines that create unwanted disulfides
Excessive hydrophobic regions causing aggregation
Poor solubility predictions

Recommended tools:

NetSolP / SoluProt - Initial solubility filtering
SolubleMPNN - Sequence redesign for improved solubility
ESM - Sequence likelihood scoring
ipTM - Interface stability assessment
pSAE - Hydrophobic exposure quantification

See

reference/protein_optimization.md

for detailed optimization workflows and tool usage.

API Reference

For complete API documentation including all endpoints, request/response formats, and authentication details, see

reference/api_reference.md

.

Examples

For concrete code examples covering common use cases (experiment submission, status tracking, result retrieval, batch processing), see

reference/examples.md

.

Important Notes

Platform is currently in alpha/beta phase with features subject to change
Not all platform features are available via API yet
Results typically delivered in ~21 days
Contact support@adaptyvbio.com for access requests or questions
Suitable for high-throughput AI-driven protein design workflows