Total 33,295 skills
Showing 12 of 33295 skills
Implement identity and access management. Use when designing authentication, authorization, or user management. Covers OAuth2, OIDC, and RBAC.
Generate git commit messages and help with git workflows
Design scalable, reliable software systems. Use when planning new systems, major features, or architecture changes. Covers C4 diagrams, trade-off analysis, and system decomposition.
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.
Break down large tasks into smaller, actionable items. Use when planning sprints, estimating work, or creating implementation plans. Covers task breakdown strategies.
Guidance for cell-free protein synthesis (CFPS) optimization. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing difficult proteins (disulfide-rich, toxic, membrane).
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
Structure prediction using Boltz-1/Boltz-2, an open biomolecular structure predictor. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For Chai prediction, use chai.
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use proteinmpnn. For solubility optimization, use solublempnn.
Design and implement agent-based models (ABM) for simulating complex systems with emergent behavior from individual agent interactions. Use when "agent-based, multi-agent, emergent behavior, swarm simulation, social simulation, crowd modeling, population dynamics, individual-based, " mentioned.
Manages architecture components, diagrams, attributes, tags, and templates via the Revision External API. Triggers when Revision API, architecture components, C4 diagrams, or syncing architecture data with Revision are mentioned.
LLM fine-tuning with LoRA, QLoRA, and instruction tuning for domain adaptation.