Total 54,003 skills, Data Processing has 2767 skills
Showing 12 of 2767 skills
Systematic ACMG/AMP variant classification using ToolUniverse tools. Given a genetic variant (HGVS, rsID, or gene+change), applies all 28 ACMG criteria (PVS1, PS1-4, PM1-6, PP1-5, BA1, BS1-4, BP1-7) through automated database queries and computational predictions. Produces a final 5-tier classification (Pathogenic / Likely Pathogenic / VUS / Likely Benign / Benign) with evidence summary. Use when asked to classify a variant, interpret a VUS, apply ACMG criteria, assess pathogenicity, or determine clinical significance of a germline variant.
Research GPCR receptors, antibody structures, and protein interface analysis using GPCRdb, SAbDab, and PDBePISA. Retrieves receptor families, known ligands (agonists/antagonists/biased), mutations, crystal/cryo-EM structures, antibody CDR annotations, and protein-protein interface geometry. Use when asked about GPCR drug targets, receptor-ligand interactions, antibody structural data, or protein assembly interfaces.
Population genetics research using the 1000 Genomes Project (IGSR) -- search populations by superpopulation ancestry (AFR, AMR, EAS, EUR, SAS), retrieve samples by population code, list available data collections, and integrate with GWAS tools for population stratification analysis. Use when users ask about 1000 Genomes populations, sample ancestry, allele frequency variation across continental groups, population-specific GWAS interpretation, or IGSR data collections like the 30x high-coverage resequencing or HGSVC.
Immunology research workflows using ToolUniverse tools. Covers antibody-antigen structural analysis (SAbDab, TheraSAbDab), immune protein interactions (IntAct, BioGRID), epitope and T-cell/B-cell assay data (IEDB), immunoglobulin gene databases (IMGT), cytokine/receptor signaling (OpenTargets, GWAS), clinical safety data for immune diseases (FAERS, clinical trials), autoimmune disease genetics (Orphanet), and immune pathway analysis (KEGG, Reactome). Use when researchers ask about antibody targets, immune signaling networks, autoimmune genetics, immunotherapy safety, epitope discovery, or immune pathway enrichment.
Ichimoku Cloud (一目均衡表) five-line system signal engine for stocks listed in HK / US / A-share / Singapore via Longbridge Securities. Computes Tenkan-sen, Kijun-sen, Senkou Span A/B, and Chikou Span from OHLCV data; generates price-vs-cloud position, line-cross signals, and full trend-confirmation scores. Triggers: "一目均衡表", "一目云", "云图", "转折线", "基准线", "先行带", "迟行线", "云上", "云下", "一目均衡表", "一目雲", "雲圖", "轉折線", "基準線", "先行帶", "遲行線", "ichimoku", "ichimoku cloud", "tenkan sen", "kijun sen", "senkou span", "chikou span", "cloud breakout".
Retrieve full historical end-of-day price data for market indices using Octagon MCP. Use when analyzing index performance over time, tracking market trends, calculating returns, and understanding market context for individual stock analysis.
Retrieve the latest stock grades and ratings from top analysts and financial institutions using Octagon MCP. Use when tracking analyst upgrades, downgrades, rating changes, and institutional sentiment over time.
Use when working with DataAsset, DataTable, soft reference, hard reference, TSoftObjectPtr, async loading, Asset Manager, StreamableManager, or game data structures in Unreal Engine. See references/asset-loading-patterns.md for async loading and StreamableManager patterns. See references/data-driven-design.md for data-driven gameplay architecture. For serialization, see ue-serialization-savegames. For C++ foundations, see ue-cpp-foundations.
Small-cap growth stock discovery — identifies overlooked small/mid-cap high-growth companies (A-share 专精特新, HK growth stocks, US small-cap growth) by screening for market cap < 5–10B, revenue growth > 30%, ROE > 15%, and low institutional ownership. Triggers: "小盘成长", "小市值", "成长股", "中小盘", "专精特新", "隐形冠军", "小盘股", "成长潜力", "小盤成長", "小市值", "成長股", "中小盤", "專精特新", "隱形冠軍", "small cap growth", "small cap stocks", "growth stocks", "mid-small cap", "hidden champions", "high growth companies", "small cap discovery", "emerging growth", "小市值成长股", "中小市值".
Cross-application GIS skill — CRS reference, data formats, Blender/QGIS integration via digitalmodel.gis
Analyze parliamentary sessions from Chile, Spain, Peru and EU. Research transcripts, identify topics and trends, generate analytical PDF reports. Also search Official Journals (BOE, EUR-Lex) for decrees, laws, resolutions and published regulations. Use when user asks about legislative sessions, committees, parliamentary debates, official journal, decrees, laws, resolutions or requests reports/analysis.
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