clinical-trials-search

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2 scripts

Search ClinicalTrials.gov with natural language queries. Find clinical trials, enrollment, and outcomes using Valyu semantic search.

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Sourceyorkeccak/scientific-skills
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NPX Install

npx skill4agent add yorkeccak/scientific-skills clinical-trials-search

Tags

Translated version includes tags in frontmatter
clinical-trials-searchsemantic-searchnatural-language-queryvalyu-apihealthcare-data-processing

SKILL.md Content

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Clinical Trials Search

Search the complete ClinicalTrials.gov database of clinical studies using natural language queries powered by Valyu's semantic search API.

Why This Skill is Powerful

  • No API Parameter Parsing: Just pass natural language queries directly - no need to construct complex search parameters
  • Semantic Search: Understands the meaning of your query, not just keyword matching
  • Full-Text Access: Returns complete trial information including phases, conditions, interventions, and outcomes
  • Image Links: Includes data visualizations when available
  • Comprehensive Coverage: Access to all ClinicalTrials.gov data

Requirements

  1. Node.js 18+ (uses built-in fetch)
  2. Valyu API key from https://platform.valyu.ai ($10 free credits)

CRITICAL: Script Path Resolution

The 
scripts/search
commands in this documentation are relative to this skill's installation directory.
Before running any command, locate the script using:
bash
CLINICAL_TRIALS_SCRIPT=$(find ~/.claude/plugins/cache -name "search" -path "*/clinical-trials-search/*/scripts/*" -type f 2>/dev/null | head -1)
Then use the full path for all commands:
bash
$CLINICAL_TRIALS_SCRIPT "CAR-T cell therapy trials" 15

API Key Setup Flow

When you run a search and receive 
"setup_required": true
, follow this flow:
  1. Ask the user for their API key: "To search ClinicalTrials.gov, I need your Valyu API key. Get one free ($10 credits) at https://platform.valyu.ai"
  2. Once the user provides the key, run:
    bash
    scripts/search setup <api-key>
  3. Retry the original search.

When to Use This Skill

  • Finding ongoing and completed clinical trials
  • Identifying trial eligibility criteria
  • Recruiting status and enrollment information
  • Comparing treatment approaches in trials
  • Patient recruitment and enrollment research
  • Outcomes and safety data from trials

Output Format

json
{
  "success": true,
  "type": "clinical_trials_search",
  "query": "CAR-T cell therapy trials",
  "result_count": 10,
  "results": [
    {
      "title": "Trial Title",
      "url": "https://clinicaltrials.gov/...",
      "content": "Trial details, phase, conditions, outcomes...",
      "source": "clinical-trials",
      "relevance_score": 0.95,
      "images": []
    }
  ],
  "cost": 0.025
}

Processing Results

With jq

bash
# Get trial titles
scripts/search "query" 10 | jq -r '.results[].title'

# Get URLs
scripts/search "query" 10 | jq -r '.results[].url'

# Extract full content
scripts/search "query" 10 | jq -r '.results[].content'

Common Use Cases

Drug Development

bash
# Find drug trials
scripts/search "phase 2 trials for Alzheimer's disease" 50

Treatment Research

bash
# Search for treatment studies
scripts/search "checkpoint inhibitor combinations in lung cancer" 20

Medical Device Studies

bash
# Find device trials
scripts/search "continuous glucose monitoring device studies" 15

Intervention Analysis

bash
# Search for intervention studies
scripts/search "behavioral interventions for obesity" 25

Error Handling

All commands return JSON with 
success
field:
json
{
  "success": false,
  "error": "Error message"
}
Exit codes:
  • 0
    - Success
  • 1
    - Error (check JSON for details)

API Endpoint

  • Base URL: 
    https://api.valyu.ai/v1
  • Endpoint: 
    /search
  • Authentication: X-API-Key header

Architecture

scripts/
├── search          # Bash wrapper
└── search.mjs      # Node.js CLI
Direct API calls using Node.js built-in 
fetch()
, zero external dependencies.

Adding to Your Project

If you're building an AI project and want to integrate Clinical Trials Search directly into your application, use the Valyu SDK:

Python Integration

python
from valyu import Valyu

client = Valyu(api_key="your-api-key")

response = client.search(
    query="your search query here",
    included_sources=["valyu/valyu-clinical-trials"],
    max_results=20
)

for result in response["results"]:
    print(f"Title: {result['title']}")
    print(f"URL: {result['url']}")
    print(f"Content: {result['content'][:500]}...")

TypeScript Integration

typescript
import { Valyu } from "valyu-js";

const client = new Valyu("your-api-key");

const response = await client.search({
  query: "your search query here",
  includedSources: ["valyu/valyu-clinical-trials"],
  maxResults: 20
});

response.results.forEach((result) => {
  console.log(`Title: ${result.title}`);
  console.log(`URL: ${result.url}`);
  console.log(`Content: ${result.content.substring(0, 500)}...`);
});
See the Valyu docs for full integration examples and SDK reference.