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Run Python scripts with uv including inline dependencies (PEP 723), temporary dependencies (--with), and ephemeral tool execution. Use when running scripts, needing one-off dependencies, or creating executable Python scripts. No venv activation required.
npx skill4agent add laurigates/claude-plugins uv-runuv run script.pyuv run --with requests script.pyuvx tool# Run script (uv manages environment automatically)
uv run script.py
# Run with arguments
uv run script.py --input data.csv --output results.json
# Run a specific module
uv run -m http.server 8000
# Run with specific Python version
uv run --python 3.12 script.py# Single dependency
uv run --with requests fetch_data.py
# Multiple dependencies
uv run --with requests --with rich api_client.py
# Version constraints
uv run --with 'requests>=2.31' --with 'rich>12,<14' script.py
# Combine with project dependencies
uv run --with pytest-benchmark pytest # Add benchmark to existing pytest#!/usr/bin/env -S uv run --script
# /// script
# requires-python = ">=3.11"
# dependencies = [
# "requests>=2.31",
# "rich>=13.0",
# ]
# ///
import requests
from rich import print
response = requests.get("https://api.github.com")
print(response.json())uv run script.py
# Or make executable:
chmod +x script.py
./script.py# Initialize script with metadata
uv init --script example.py --python 3.12
# Add dependency to script
uv add --script example.py requests rich
# Lock script dependencies for reproducibility
uv lock --script example.py# Run tool once
uvx pycowsay "Hello from uv!"
uvx httpie https://api.github.com
uvx ruff check .
# With specific version
uvx ruff@0.1.0 check .
# uvx is shorthand for:
uv tool run pycowsay "Hello"#!/usr/bin/env -S uv run --script
# /// script
# dependencies = ["click", "rich"]
# ///
import click
from rich import print
@click.command()
@click.argument('name')
def hello(name):
print(f"[green]Hello, {name}![/green]")
if __name__ == "__main__":
hello()#!/usr/bin/env -S uv run --script --python 3.12
# /// script
# requires-python = ">=3.12"
# dependencies = ["httpx"]
# ///
import httpx
# Uses Python 3.12+ features| Scenario | Approach |
|---|---|
| Quick one-off task | |
| Reusable script | Inline deps (PEP 723) |
| Shareable utility | PEP 723 + shebang |
| Team collaboration | Inline deps + |
| Run CLI tool once | |
| Project scripts | |
uvx tooluvx ruff check .uv run --with pkguv run --with requests script.py# Run a tool (CLI application)
uvx httpie https://api.github.com
# Run a script with dependencies
uv run --with httpx api_test.py# CPU profiling
uv run python -m cProfile -s cumtime script.py | head -20
# Line-by-line profiling (temporary dependency)
uv run --with line-profiler kernprof -l -v script.py
# Memory profiling
uv run --with memory-profiler python -m memory_profiler script.py
# Real-time profiling (ephemeral tool)
uvx py-spy top -- python script.py
# Quick profiling
uv run --with scalene python -m scalene script.py