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ChineseBio-Research Start
生物研究入门
If you see unfamiliar placeholders or need to check which tools are connected, see CONNECTORS.md.
You are helping a biological researcher get oriented with the bio-research plugin. Walk through the following steps in order.
若你看到不熟悉的占位符或需要检查已连接的工具,请查看 CONNECTORS.md。
你将协助一位生物研究人员熟悉生物研究插件,请按以下步骤依次操作。
Step 1: Welcome
步骤1:欢迎语
Display this welcome message:
Bio-Research Plugin
Your AI-powered research assistant for the life sciences. This plugin brings
together literature search, data analysis pipelines,
and scientific strategy — all in one place.显示以下欢迎信息:
生物研究插件
你的生命科学AI研究助手。该插件集文献检索、数据分析流程
和科研策略于一体,一站式满足你的需求。Step 2: Check Available MCP Servers
步骤2:检查可用MCP服务器
Test which MCP servers are connected by listing available tools. Group the results:
Literature & Data Sources:
- ~~literature database — biomedical literature search
- ~~literature database — preprint access (biology and medicine)
- ~~journal access — academic publications
- ~~data repository — collaborative research data (Sage Bionetworks)
Drug Discovery & Clinical:
- ~~chemical database — bioactive compound database
- ~~drug target database — drug target discovery platform
- ClinicalTrials.gov — clinical trial registry
- ~~clinical data platform — clinical trial site ranking and platform help
Visualization & AI:
- ~~scientific illustration — create scientific figures and diagrams
- ~~AI research platform — AI for biology (histopathology, drug discovery)
Report which servers are connected and which are not yet set up.
通过列出可用工具来测试已连接的MCP服务器,并对结果进行分组:
文献与数据源:
- ~~文献数据库——生物医学文献检索
- ~~文献数据库——预印本访问(生物学与医学领域)
- ~~期刊访问——学术出版物获取
- ~~数据仓库——协作研究数据(Sage Bionetworks)
药物研发与临床:
- ~~化合物数据库——生物活性化合物数据库
- ~~药物靶点数据库——药物靶点发现平台
- ClinicalTrials.gov——临床试验注册库
- ~~临床数据平台——临床试验站点排名与平台辅助
可视化与AI:
- ~~科学绘图——创建科学图表与示意图
- ~~AI研究平台——生物学AI工具(组织病理学、药物研发方向)
汇报哪些服务器已连接,哪些尚未设置。
Step 3: Survey Available Skills
步骤3:调研可用分析技能
List the analysis skills available in this plugin:
| Skill | What It Does |
|---|---|
| Single-Cell RNA QC | Quality control for scRNA-seq data with MAD-based filtering |
| scvi-tools | Deep learning for single-cell omics (scVI, scANVI, totalVI, PeakVI, etc.) |
| Nextflow Pipelines | Run nf-core pipelines (RNA-seq, WGS/WES, ATAC-seq) |
| Instrument Data Converter | Convert lab instrument output to Allotrope ASM format |
| Scientific Problem Selection | Systematic framework for choosing research problems |
列出该插件中可用的分析技能:
| Skill | 功能 |
|---|---|
| Single-Cell RNA QC | 基于MAD过滤的scRNA-seq数据质量控制 |
| scvi-tools | 单细胞组学深度学习工具(scVI、scANVI、totalVI、PeakVI等) |
| Nextflow Pipelines | 运行nf-core流程(RNA-seq、WGS/WES、ATAC-seq) |
| Instrument Data Converter | 将实验室仪器输出转换为Allotrope ASM格式 |
| Scientific Problem Selection | 选择研究课题的系统化框架 |
Step 4: Optional Setup — Binary MCP Servers
步骤4:可选设置——二进制MCP服务器
Mention that two additional MCP servers are available as separate installations:
- ~~genomics platform — Access cloud analysis data and workflows
Install: Download from https://github.com/10XGenomics/txg-mcp/releases
txg-node.mcpb - ~~tool database (Harvard MIMS) — AI tools for scientific discovery
Install: Download from https://github.com/mims-harvard/ToolUniverse/releases
tooluniverse.mcpb
These require downloading binary files and are optional.
提及还有两个额外的MCP服务器可单独安装:
- ~~genomics platform — 访问云分析数据与工作流 安装:从https://github.com/10XGenomics/txg-mcp/releases下载`txg-node.mcpb`
- ~~tool database (Harvard MIMS) — 用于科学发现的AI工具 安装:从https://github.com/mims-harvard/ToolUniverse/releases下载`tooluniverse.mcpb`
这些需要下载二进制文件,属于可选组件。
Step 5: Ask How to Help
步骤5:询问需求
Ask the researcher what they're working on today. Suggest starting points based on common workflows:
- Literature review — "Search ~~literature database for recent papers on [topic]"
- Analyze sequencing data — "Run QC on my single-cell data" or "Set up an RNA-seq pipeline"
- Drug discovery — "Search ~~chemical database for compounds targeting [protein]" or "Find drug targets for [disease]"
- Data standardization — "Convert my instrument data to Allotrope format"
- Research strategy — "Help me evaluate a new project idea"
Wait for the user's response and guide them to the appropriate tools and skills.
询问研究人员当前的工作内容。根据常见工作流提供起始建议:
- 文献综述 — "检索~~文献数据库中关于[主题]的近期论文"
- 测序数据分析 — "对我的单细胞数据进行QC检查" 或 "搭建RNA-seq分析流程"
- 药物研发 — "在~~化合物数据库中检索靶向[蛋白质]的化合物" 或 "寻找针对[疾病]的药物靶点"
- 数据标准化 — "将我的仪器数据转换为Allotrope格式"
- 科研策略 — "帮我评估一个新的项目想法"
等待用户回复并引导他们使用合适的工具与技能。