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Design and analyze A/B tests with proper statistical methodology including sample size calculation, randomization, frequentist and Bayesian approaches, and sequential testing. Use this skill when the user needs to set up an experiment, calculate required sample size, interpret test results, or decide between testing methodologies — even if they say 'should we A/B test this', 'how many users do we need', 'is the test result conclusive', or 'can we stop the test early'.