Search Results: drug-target-prioritization

Found 2 Skills

Data Processingmims-harvard/tooluniverse

tooluniverse-crispr-screen-analysis

Comprehensive analysis of CRISPR knockout/activation screens with gene essentiality scoring, pathway enrichment, functional annotation, and therapeutic target identification. Identifies essential genes, synthetic lethal interactions, and actionable drug targets from pooled or arrayed CRISPR screens. Use when analyzing CRISPR screen data, identifying gene dependencies, or prioritizing hits for validation.

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Data Processingmims-harvard/tooluniverse

tooluniverse-gwas-trait-to-gene

Discover genes associated with diseases and traits using GWAS data from the GWAS Catalog (500,000+ associations) and Open Targets Genetics (L2G predictions). Identifies genetic risk factors, prioritizes causal genes via locus-to-gene scoring, and assesses druggability. Use when asked to find genes associated with a disease or trait, discover genetic risk factors, translate GWAS signals to gene targets, or answer questions like "What genes are associated with type 2 diabetes?"

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