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Found 122 Skills
Use when working with fundamental software development knowledge — patterns, algorithms, architecture, and craftsmanship principles drawn from canonical published works. USE FOR: development fundamentals, pattern selection, architecture decisions, algorithm choice, code quality principles, choosing between architectural styles DO NOT USE FOR: specific pattern implementations (use sub-skills: design-patterns, integration-patterns, algorithms, etc.), testing strategy (use testing), infrastructure (use iac)
Data structures and algorithms reference based on CLRS. Use this skill when implementing, discussing, or choosing data structures or algorithms. Auto-activates for algorithm selection, complexity analysis, and performance optimization. Comprehensive coverage of fundamental and advanced data structures with pseudocode examples.
Comprehensive guide for creating software diagrams using Mermaid syntax. Use when users need to create, visualize, or document software through diagrams including class diagrams (domain modeling, object-oriented design), sequence diagrams (application flows, API interactions, code execution), flowcharts (processes, algorithms, user journeys), entity relationship diagrams (database schemas), C4 architecture diagrams (system context, containers, components), state diagrams, git graphs, pie charts, gantt charts, or any other diagram type. Triggers include requests to "diagram", "visualize", "model", "map out", "show the flow", or when explaining system architecture, database design, code structure, or user/application flows.
Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. Best for proteomics, comprehensive MS data processing. For simple spectral comparison and metabolite ID use matchms.
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.
In-memory caching in Golang using samber/hot — eviction algorithms (LRU, LFU, TinyLFU, W-TinyLFU, S3FIFO, ARC, TwoQueue, SIEVE, FIFO), TTL, cache loaders, sharding, stale-while-revalidate, missing key caching, and Prometheus metrics. Apply when using or adopting samber/hot, when the codebase imports github.com/samber/hot, or when the project repeatedly loads the same medium-to-low cardinality resources at high frequency and needs to reduce latency or backend pressure.
Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.
Implement quiz game logic including game creation, player turn management, score calculation, answer validation, and game completion. Use when building game flows, turn-based mechanics, and scoring algorithms.
Process data with custom algorithms
Hardware-agnostic quantum ML framework with automatic differentiation. Use when training quantum circuits via gradients, building hybrid quantum-classical models, or needing device portability across IBM/Google/Rigetti/IonQ. Best for variational algorithms (VQE, QAOA), quantum neural networks, and integration with PyTorch/JAX/TensorFlow. For hardware-specific optimizations use qiskit (IBM) or cirq (Google); for open quantum systems use qutip.
Implement Syncfusion Windows Forms TreeMap control for hierarchical data visualization with nested rectangles. Use this when working with TreeMap controls, hierarchical data display, space-efficient charts, or color-coded visualizations. Covers TreeMap configuration, layout algorithms, color mapping, and customization for stock market visualizations and data categorization with rectangular layouts.