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Found 10,528 Skills
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
Debug Streamlit frontend and backend changes using make debug with hot-reload. Use when testing code changes, investigating bugs, checking UI behavior, or needing screenshots of the running app.
Flutter开发完整指南：Clean Architecture架构规范、TDD测试工作流、BLoC状态管理、故障排除与代码生成
Fetches a Jira ticket and starts implementation with a branch and plan. Use when (1) starting work on a Jira ticket, (2) creating a feature branch from a Jira issue, (3) beginning implementation of a story or task, (4) picking up a ticket from the backlog, or (5) user provides a Jira ticket ID to work on.
Creates a new album with the correct directory structure and templates. Use IMMEDIATELY when the user says 'make a new album' or similar, before any discussion.
Create meeting report entries in the Notion meeting reports database. Use when the user asks to create a meeting report, log a meeting, or add a meeting to Notion. Requires Notion MCP.
Orchestrate multiple independent agents running simultaneously, leveraging Claude Sonnet 4.5's parallel tool execution capabilities to maximize throughput on multi-task requests.
Add new features to Syncpack including commands and validation logic. Use when implementing new CLI commands, adding InstanceState variants, or extending version group behaviour.
Design PM-friendly technical architecture for features. No code, only high-level design decisions.
Check reference SDK implementations using btca ask
MANDATORY before starting any task. Enforces the GPA execution loop that prevents tool call sprawl. G: GATHER phase combines discover queries + memory reads + file reads into one phase. P: Plan in text with zero tool calls. A: APPLY all writes/edits/verification in one phase. One call per tool type per phase — batch all same-type operations together. Covers dependency analysis, batch opportunities, scope estimation, and loop-back triggers.
Ensure AI agents work in an isolated Git worktree to prevent changes to the main working directory. Use when AI is about to make its first code modification in a session, or when the user requests isolated/safe editing. Triggers include starting to edit files, implementing features, or fixing bugs.