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Found 1,381 Skills
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.
Direct REST API access to UniProt. Protein searches, FASTA retrieval, ID mapping, Swiss-Prot/TrEMBL. For Python workflows with multiple databases, prefer bioservices (unified interface to 40+ services). Use this for direct HTTP/REST work or UniProt-specific control.
CCXT cryptocurrency trading library. Use for cryptocurrency exchange APIs, trading, market data, order management, and crypto trading automation across 150+ exchanges. Supports JavaScript/Python/PHP.
Expert FastAPI developer specializing in production-ready async REST APIs with Pydantic v2, SQLAlchemy 2.0, OAuth2/JWT authentication, and comprehensive security. Deep expertise in dependency injection, background tasks, async database operations, input validation, and OWASP security best practices. Use when building high-performance Python web APIs, implementing authentication systems, or securing API endpoints.
Production-grade backend service development across Node.js (Express/Fastify/NestJS/Hono), Bun, Python (FastAPI), Go, and Rust (Axum), with PostgreSQL and common ORMs (Prisma/Drizzle/SQLAlchemy/GORM/SeaORM). Use for REST/GraphQL/tRPC APIs, auth (OIDC/OAuth), caching, background jobs, observability (OpenTelemetry), testing, deployment readiness, and zero-trust defaults.
World-class backend engineering - distributed systems, database architecture, API design, and the battle scars from scaling systems that handle millions of requestsUse when "backend, api, database, postgres, mysql, mongodb, redis, graphql, rest, authentication, authorization, caching, queue, background job, webhook, migration, transaction, n+1, rate limit, server, node.js, python, go, backend, api, database, architecture, performance, reliability, security" mentioned.
Use when CONFIGURING an existing SDK - NOT for initial generation. Covers gen.yaml configuration for all languages: TypeScript, Python, Go, Java, C#, PHP, Ruby. Also covers runtime overrides (retries, timeouts, server selection) in application code. Triggers on "configure SDK", "gen.yaml", "SDK options", "SDK config", "SDK configuration", "runtime override", "SDK client config", "override timeout", "per-call config". For NEW SDK generation, use start-new-sdk-project instead.
Language-specific coding standards and validation rules. Provides Python, Go, Rust, TypeScript, Shell, YAML, JSON, and Markdown standards. Auto-loaded by /vibe, /implement, /doc, /bug-hunt, /complexity based on file types.
Python/pytest TDD specialist for test-driven development workflows. Use when writing tests, auditing test quality, running pytest, or generating test reports. Integrates with uv and pyproject.toml configuration.
Use when generating PDFs from markdown with Pandoc - covers differences from Python-Markdown, blank line rules, fix scripts for labels/anchors/metadata, and visual testing workflow
Use when building distributed apps with Aspire; orchestrating .NET, JavaScript, Python, or polyglot services; when environment variables or service discovery aren't working; when migrating from .NET Aspire 9 to 13+ or Community Toolkit; when seeing AddNpmApp deprecated errors; when OTEL not appearing in dashboard; when ports change on restart breaking OAuth; when configuring MCP server for AI assistants; when debugging Aspire apps and need to check resource status or logs
Writing optimized, secure, multi-stage Dockerfiles with language-specific patterns (Python, Node.js, Go, Rust), BuildKit features, and distroless images. Use when containerizing applications, optimizing existing Dockerfiles, or reducing image sizes.