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Found 98 Skills
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.
Provide actionable treatment recommendations for cancer patients based on molecular profile. Interprets tumor mutations, identifies FDA-approved therapies, finds resistance mechanisms, matches clinical trials. Use when oncologist asks about treatment options for specific mutations (EGFR, KRAS, BRAF, etc.), therapy resistance, or clinical trial eligibility.
Build and troubleshoot Syncfusion Blazor diagrams using SfDiagramComponent. Trigger for flowcharts, org charts, mind maps, BPMN, UML sequence, swimlanes, symbol palettes, nodes/connectors/ports/annotations, layouts, data binding, serialization (load/save), export/print, and collaborative editing questions. Provide Blazor + Syncfusion setup steps, configuration patterns, and sample snippets.
Research and analyze tokens on supported blockchains: search tokens by keyword, get token details (price, market cap, volume, supply), run security audits (honeypot, mint risk, proxy, tax), list DEX liquidity pools, view top holders, find smart money traders, and retrieve K-line candlestick chart data. Trigger words: token, coin, search token, find token, look up token, token info, token details, token data, token price, price of, how much is, what is the price, market cap, market capitalization, volume, trading volume, supply, total supply, circulating supply, FDV, fully diluted valuation, token security, security audit, is it safe, honeypot, rug pull, mint risk, proxy contract, buy tax, sell tax, token pools, liquidity pools, DEX pools, trading pools, LP, liquidity, token holders, top holders, who holds, whale holders, holder distribution, token traders, smart money, smart traders, KOL traders, top traders, candles, candlestick, K-line, kline, price chart, price history, OHLCV, token analysis, token research, due diligence, DYOR, check token. Chinese: 代币, 搜索代币, 查代币, 代币信息, 代币详情, 代币价格, 价格多少, 市值, 交易量, 总供应量, 代币安全, 安全审计, 是否安全, 蜜罐, 貔貅, 池子, 流动性, 持有者, 大户, 鲸鱼, 交易者, 聪明钱, K线, 蜡烛图, 价格走势. CRITICAL: Always use `--json` flag for structured output. CRITICAL: When user asks about token safety, ALWAYS run `token security` — do not guess. Do NOT use this skill for: - Trending token rankings or new token discovery → use liberfi-market - Wallet holdings, activity, or PnL stats → use liberfi-portfolio - Swap quotes, trade execution, or transaction broadcast → use liberfi-swap - General market trends without a specific token → use liberfi-market Do NOT activate on vague single-word inputs like "token" or "coin" without additional context specifying a search query, chain, or address.
Implements the Syncfusion WPF DatePicker (SfDatePicker) control for touch-friendly date selection. Use this when adding date input controls, customizing date picker appearance, formatting date displays, or restricting date ranges in WPF applications. Covers installation, date formatting, styling, customization, value management, and event handling.
Display and manipulate PDF documents using PDFKit. Use when embedding PDFView to show PDF files, creating or modifying PDFDocument instances, adding annotations (highlights, notes, signatures), extracting text with PDFSelection, navigating pages, generating thumbnails, filling PDF forms, or wrapping PDFView in SwiftUI.
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.
Implements Syncfusion WinUI DatePicker (SfDatePicker) control for date input and selection in desktop applications. Use this when building date input controls, calendar dropdown pickers, or date selection interfaces. This skill covers date restrictions, date formatting, calendar types, dropdown spinners, localization, and blackout dates for WinUI applications.
Parse documents into clean markdown or structured JSON via the xparse-cli. Use this skill when the user provides a PDF, image, Office file, HTML, OFD, or other supported document and wants it read, converted, summarized, or prepared for downstream agent use. Handles encrypted PDFs, page ranges, markdown/text output, and detailed structured extraction. Prefer this skill whenever the task starts from a local file or document URL and the first step is to turn it into agent-friendly content rather than manually inspect the raw file.
MUST activate when the user wants to build, create, or generate a React application, React app, web application, single-page application (SPA), or frontend application — even if no project files exist yet. MUST also activate when the project contains a uiBundles/*/src/ directory or sfdx-project.json and the prompt says create, build, construct, or generate a new app, site, or page from scratch — even if the prompt also describes visual styling. MUST also activate when the task spans more than one ui-bundle skill. Use this skill when building a complete app end-to-end. This is the orchestrator that coordinates scaffolding, features, data access, frontend UI, integrations, and deployment in the correct dependency order. Without it, phases execute out of order and the app breaks. Do NOT use for Lightning Experience apps with custom objects (use generating-lightning-app). Do NOT use for single-concern edits to an existing page (use building-ui-bundle-frontend).
Build and troubleshoot barcode generation in Blazor using SfBarcodeGenerator, SfQRCodeGenerator, and SfDataMatrixGenerator. Trigger for 1D barcodes (Code39, Code128, Codabar), QR codes with logo and error correction, Data Matrix, checksum validation, and exporting barcodes to images in Syncfusion Blazor apps.