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Found 142 Skills
Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
Comprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems. Use when users need help with ISO 13485 QMS documentation, including (1) conducting gap analysis of existing documentation, (2) creating Quality Manuals, (3) developing required procedures and work instructions, (4) preparing Medical Device Files, (5) understanding ISO 13485 requirements, or (6) identifying missing documentation for medical device certification. Also use when users mention medical device regulations, QMS certification, FDA QMSR, EU MDR, or need help with quality system documentation.
Full STRIDE-A threat model analysis and incremental update skill for repositories and systems. Supports two modes: (1) Single analysis — full STRIDE-A threat model of a repository, producing architecture overviews, DFD diagrams, STRIDE-A analysis, prioritized findings, and executive assessments. (2) Incremental analysis — takes a previous threat model report as baseline, compares the codebase at the latest (or a given commit), and produces an updated report with change tracking (new, resolved, still-present threats), STRIDE heatmap, findings diff, and an embedded HTML comparison. Only activate when the user explicitly requests a threat model analysis, incremental update, or invokes /threat-model-analyst directly.
Generate Office documents (DOCX, XLSX, PDF, PPTX) with TypeScript. Pure JS libraries that work everywhere: Claude Code CLI, Cloudflare Workers, browsers. Uses docx (Word), xlsx/SheetJS (Excel), pdf-lib (PDF), pptxgenjs (PowerPoint). Use when: creating invoices, reports, spreadsheets, presentations, form filling, exporting data to Office formats, or troubleshooting "Packer.toBuffer", "XLSX.utils", "PDFDocument", "pptxgenjs" errors.
Parse documents into clean markdown or structured JSON via the xparse-cli. Use this skill when the user provides a PDF, image, Office file, HTML, OFD, or other supported document and wants it read, converted, summarized, or prepared for downstream agent use. Handles encrypted PDFs, page ranges, markdown/text output, and detailed structured extraction. Prefer this skill whenever the task starts from a local file or document URL and the first step is to turn it into agent-friendly content rather than manually inspect the raw file.
12 production-ready regulatory affairs and quality management skills for HealthTech/MedTech: ISO 13485 QMS, MDR 2017/745, FDA 510(k)/PMA, ISO 27001 ISMS, GDPR/DSGVO compliance, risk management (ISO 14971), CAPA, document control, and internal auditing. Python tools included (all stdlib-only). Works with Claude Code, Codex CLI, and OpenClaw.
End-to-end drug discovery platform combining ChEMBL compounds, DrugBank, targets, and FDA labels. Natural language powered by Valyu.
Complete biomedical information search combining PubMed, preprints, clinical trials, and FDA drug labels. Powered by Valyu semantic search.
HOWL v2 — Hunt, Optimize, Win, Learn. Nightly self-improvement loop for the WOLF autonomous trading strategy. Runs once per day (via cron) to review all trades from the last 24 hours, compute win rates, analyze signal quality correlation, evaluate DSL tier performance, identify missed opportunities, and produce concrete improvement suggestions for the wolf-strategy skill. v2 adds fee drag ratio (FDR) analysis, holding period bucketing, LONG vs SHORT regime detection, rotation cost tracking, cumulative drift detection, and gross vs net profit factor separation. Use when setting up daily trade review automation, analyzing trading performance, or improving an autonomous trading strategy through data-driven feedback loops. Requires Senpi MCP connection, mcporter CLI, and OpenClaw cron system.
Identify, validate, and ship production-safe Node.js optimizations with execution time as the primary objective. Use when users ask to reduce latency (p50/p95/p99), improve throughput, and then reduce CPU/memory/event-loop lag/FD pressure or retry amplification, using one-PR-per-improvement workflows with benchmarks.
Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
Enable efficient communication between Thai-language users and agents by translating Thai prompts into English in two modes and by preventing Thai text corruption in files. Use when the user writes in Thai, asks for Thai-to-English interpretation, wants token-efficient prompt rewriting, or reports mojibake/replacement-character issues such as U+FFFD in saved files.