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Found 139 Skills
Audio playback using Tone.js including players, transport, scheduling, and loading audio. Use when implementing background music, sound effects, audio synchronization, or timed audio events. Essential for any audio-enabled web application.
Prioritize drug targets from a ranked gene list (e.g., scRNA-seq DE output) by orchestrating parallel API queries against UniProt, OpenTargets (with integrated DepMap CRISPR essentiality + gnomAD constraint), PubMed, the Human Protein Atlas (HPA), and ChEMBL tool compounds, then re-ranking by a composite score combining protein localization, druggability, disease genetics, tissue specificity (safety), focus-cell-type expression, CRISPR essentiality, LoF safety constraint, and research maturity. Use whenever the user wants to filter, triage, prioritize, or "do due diligence" on a list of candidate genes for drug discovery, especially after a DE / DEG analysis when they say things like "which of these should I follow up on", "filter for druggable targets", "make a target dossier", "rank these for tractability", "annotate these genes for druggability", or "build a target report". Trigger even when the user says just "filter these candidate genes" or hands over a CSV from a DE pipeline.
Comprehensive guide for implementing Syncfusion aspnetcore dropdown components including DropDownList, MultiSelect, AutoComplete, Mention. Single and multiple selection control with data binding, filtering, grouping, templates, and accessibility features. Essential for building professional dropdown interfaces with server-side data binding.
Implement Syncfusion DropdownList component in ASP.NET Core immediately. Single selection control with data binding, filtering, grouping, templates, and accessibility features. Essential for building professional dropdown interfaces with server-side data binding.
Proactive context window management via token monitoring, intelligent extraction, and selective rehydration. Features predictive budget monitoring, context health indicators, and priority-based retention. Use when approaching token limits or needing to preserve essential context. Complements /transcripts and PreCompact hook with proactive optimization.
Freedom of Information Act (FOIA) and public records request workflows. Use when drafting records requests, tracking submissions, understanding exemptions, appealing denials, or managing large document productions. Essential for investigative journalists, researchers, and transparency advocates.
Structure stories around essential emotional moments using Rodriguez's approach integrated with elemental genres. Use when plotting feels mechanical, when emotional beats need defining, or when building stories from vivid scenes rather than plot outlines.
Use when receiving code review feedback (especially if unclear or technically questionable), when completing tasks or major features requiring review before proceeding, or before making any completion/success claims. Covers three practices - receiving feedback with technical rigor over performative agreement, requesting reviews via code-reviewer subagent, and verification gates requiring evidence before any status claims. Essential for subagent-driven development, pull requests, and preventing false completion claims.
Email newsletter workflows for journalists and researchers. Use when creating, managing, or optimizing email newsletters, building subscriber lists, designing email templates, analyzing engagement metrics, or planning newsletter content calendars. Essential for independent journalists, academic communicators, and media organizations building direct audience relationships.
This skill should be used when working with Graphite (gt) for stacked pull requests. Use when users mention gt commands, stack management, PR workflows, or when dealing with dependent branches. Essential for understanding stack navigation, branch relationships, and Graphite's mental model.
Use when working with fundamental CLI tools and utilities that are essential for software development across all languages and platforms. Covers shells, version control, system package managers, containers, remote access, HTTP clients, data processing, and build runners. USE FOR: CLI tools, developer tooling, shell scripting, version control, system package managers, containers, remote access, build automation, text processing, choosing cross-platform dev tools DO NOT USE FOR: language-specific package managers (use language-specific skills like npm/pip/cargo), IDE configuration, language-specific build tools (use language-specific skills)
Complete ClickHouse operations guide for DevOps and SRE teams managing production deployments. Provides practical guidance on monitoring essential metrics (query latency, throughput, memory, disk), introspecting system tables, performance analysis, scaling strategies (vertical and horizontal), backup/disaster recovery, tuning at query/server/table levels, and troubleshooting common issues. Use when diagnosing ClickHouse problems, optimizing performance, planning capacity, setting up monitoring, implementing backups, or managing production clusters. Includes resource management strategies for disk space, connections, and background operations plus production checklists.