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Found 200 Skills
Guidance for implementing high-performance portfolio optimization using Python C extensions. This skill applies when tasks require optimizing financial computations (matrix operations, covariance calculations, portfolio risk metrics) by implementing C extensions for Python. Use when performance speedup requirements exist (e.g., 1.2x or greater) and the task involves numerical computations on large datasets (thousands of assets).
End-to-end data science and ML engineering workflows: problem framing, data/EDA, feature engineering (feature stores), modelling, evaluation/reporting, plus SQL transformations with SQLMesh. Use for dataset exploration, feature design, model selection, metrics and slice analysis, model cards/eval reports, experiment reproducibility, and production handoff (monitoring and retraining).
Tests applications using the Pest 4 PHP framework. Activates when writing tests, creating unit or feature tests, adding assertions, testing Livewire components, browser testing, debugging test failures, working with datasets or mocking; or when the user mentions test, spec, TDD, expects, assertion, coverage, or needs to verify functionality works.
Industry-standard gradient boosting libraries for tabular data and structured datasets. XGBoost and LightGBM excel at classification and regression tasks on tables, CSVs, and databases. Use when working with tabular machine learning, gradient boosting trees, Kaggle competitions, feature importance analysis, hyperparameter tuning, or when you need state-of-the-art performance on structured data.
This skill should be used when working with pre-trained transformer models for natural language processing, computer vision, audio, or multimodal tasks. Use for text generation, classification, question answering, translation, summarization, image classification, object detection, speech recognition, and fine-tuning models on custom datasets.
Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare datasets (MIMIC-III/IV, eICU, OMOP), or implementing deep learning models for healthcare applications (RETAIN, SafeDrug, Transformer, GNN).
This skill should be used when working with annotated data matrices in Python, particularly for single-cell genomics analysis, managing experimental measurements with metadata, or handling large-scale biological datasets. Use when tasks involve AnnData objects, h5ad files, single-cell RNA-seq data, or integration with scanpy/scverse tools.
Automated hypothesis generation and testing using large language models. Use this skill when generating scientific hypotheses from datasets, combining literature insights with empirical data, testing hypotheses against observational data, or conducting systematic hypothesis exploration for research discovery in domains like deception detection, AI content detection, mental health analysis, or other empirical research tasks.
Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create visualizations of big data, or build ML pipelines that don't fit in memory.
Guidance for counting tokens in datasets, particularly from HuggingFace or similar sources. This skill should be used when tasks involve counting tokens in datasets, understanding dataset schemas, filtering by categories/domains, or working with tokenizers. It helps avoid common pitfalls like incomplete field identification and ambiguous terminology interpretation.
Use bigquery CLI (instead of `bq`) for all Google BigQuery and GCP data warehouse operations including SQL query execution, data ingestion (streaming insert, bulk load, JSONL/CSV/Parquet), data extraction/export, dataset/table/view management, external tables, schema operations, query templates, cost estimation with dry-run, authentication with gcloud, data pipelines, ETL workflows, and MCP/LSP server integration for AI-assisted querying and editor support. Modern Rust-based replacement for the Python `bq` CLI with faster startup, better cost awareness, and streaming support. Handles both small-scale streaming inserts (<1000 rows) and large-scale bulk loading (>10MB files), with support for Cloud Storage integration.
Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. This skill provides access to 600+ scientific tools including machine learning models, datasets, APIs, and analysis packages. Use when searching for scientific tools, executing computational biology workflows, composing multi-step research pipelines, accessing databases like OpenTargets/PubChem/UniProt/PDB/ChEMBL, performing tool discovery for research tasks, or integrating scientific computational resources into LLM workflows.