Loading...
Loading...
Found 60 Skills
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.
Provide actionable treatment recommendations for cancer patients based on molecular profile. Interprets tumor mutations, identifies FDA-approved therapies, finds resistance mechanisms, matches clinical trials. Use when oncologist asks about treatment options for specific mutations (EGFR, KRAS, BRAF, etc.), therapy resistance, or clinical trial eligibility.
QCSD Refinement phase swarm for Sprint Refinement sessions using SFDIPOT product factors, BDD scenario generation, and requirements validation.
Identify, validate, and ship production-safe Node.js optimizations with execution time as the primary objective. Use when users ask to reduce latency (p50/p95/p99), improve throughput, and then reduce CPU/memory/event-loop lag/FD pressure or retry amplification, using one-PR-per-improvement workflows with benchmarks.
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.
Provides expertise for analyzing DWARF debug files and understanding the DWARF debug format/standard (v3-v5). Triggers when understanding DWARF information, interacting with DWARF files, answering DWARF-related questions, or working with code that parses DWARF data.
Performs fast file discovery with parallel search and smart defaults. Use this skill when searching for files by name, pattern, or type, especially when performance matters or when working with large directories
Senior Regulatory Affairs Manager for HealthTech and MedTech companies. Provides regulatory strategy development, submission management, pathway analysis, global compliance coordination, and cross-functional team leadership.
Expert guidance for Salesforce DX development with modern tooling, source-driven development, and CI/CD best practices
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design. For QC thresholds, use protein-qc.
Standardized template for campaign compliance intake, reviews, and approvals.