Loading...
Loading...
Found 47 Skills
Regulatory variant interpretation -- GWAS association lookup, eQTL analysis, chromatin state annotation, regulatory element overlap, and trait ontology resolution. Connects GWAS Catalog, GTEx, ENCODE, RegulomeDB, OpenTargets, OLS ontology, and Ensembl regulatory features. Use when users ask about non-coding variants, GWAS hits, eQTLs, regulatory elements, enhancer/promoter variants, or trait-associated SNPs.
Converts any Claude Code skills repository into an official plugin marketplace. Analyzes existing skills, generates .claude-plugin/marketplace.json conforming to the Anthropic spec, validates with `claude plugin validate`, tests real installation, and creates a PR to the upstream repo. Encodes hard-won anti-patterns from real marketplace development (schema traps, version semantics, description pitfalls). Use when the user mentions: marketplace, plugin support, one-click install, marketplace.json, plugin distribution, auto-update, or wants a skills repo installable via `claude plugin install`. Also trigger when the user has a skills repo and asks about packaging, distribution, or making it installable.
Search 78 public scientific, biomedical, materials science, and economic databases via REST APIs. Covers physics/astronomy (NASA, NIST, SDSS, SIMBAD), earth/environment (USGS, NOAA, EPA), chemistry/drugs (PubChem, ChEMBL, DrugBank, FDA, KEGG, ZINC, BindingDB), materials (Materials Project, COD), biology/genomics (Reactome, UniProt, STRING, Ensembl, NCBI Gene, GEO, GTEx, PDB, AlphaFold, InterPro, BioGRID, Gene Ontology, dbSNP, gnomAD, ENCODE, Human Protein Atlas, Human Cell Atlas), disease/clinical (COSMIC, Open Targets, ClinicalTrials.gov, OMIM, ClinVar, GDC/TCGA, cBioPortal, DisGeNET, GWAS Catalog), regulatory (FDA, USPTO, SEC EDGAR), economics/finance (FRED, World Bank, US Treasury), demographics (US Census, Eurostat, WHO). Use when looking up compounds, genes, proteins, pathways, variants, clinical trials, patents, economic indicators, or any public database API query.
Apply when you catch yourself writing the same instruction a second time, or notice a recurring correction. Encode the rule as a lint, metadata flag, runtime check, or script instead of more text.
Comprehensive epigenomics and gene regulation analysis integrating ENCODE functional genomics data, JASPAR transcription factor binding motifs, SCREEN cis-regulatory elements, ReMap TF binding sites, RegulomeDB variant regulatory scoring, 4D Nucleome chromatin conformation, and Ensembl regulatory features. Performs regulatory element cataloging, transcription factor analysis, variant regulatory impact scoring, chromatin conformation mapping, and gene-centric regulatory landscape profiling. Use when asked about gene regulation, enhancers, promoters, transcription factor binding, epigenetic modifications, chromatin structure, regulatory variants, or non-coding genome function.
Use when the user has one or more video clips and wants to add post-production on top — AI-generated cover as first frame, HTML/CSS captions synced to SRT, kinetic illustration overlays at hook moments, chapter chips, end-card CTA, or any other timed motion graphics. Most often used as the downstream of `/wjs-segmenting-video` — pick up where that skill stopped (raw cropped clip + per-clip SRT) and produce the upload-ready MP4. Backed by HyperFrames so everything compiles to ONE final encode — no cascade of re-encodes. Triggers — "加封面", "加字幕", "加动画", "加 CTA", "做后期", "post-production", "title card", "kinetic captions", "end card".
Cognitive memory management — encode, recall, forget, set reminders, and maintain long-term knowledge using personality-modulated memory.
When the user repeats the same correction or convention multiple times, suggest a Cursor rule to encode it permanently.
Use when the user has a video + an SRT and wants the subtitles either burned into the pixels (libass, always-visible) or soft-muxed as a togglable track. Also handles the final composite step for the localization pipeline — burn subs, mix a dub track, and keep the original audio as a low-volume bed, all in ONE ffmpeg encode (no cascade). Verifies libass availability and auto-downloads a static evermeet ffmpeg build when Homebrew's stripped binary lacks it. Triggers — "烧字幕", "硬字幕", "burn subtitles", "burn-in subs", "embed subtitle", "soft mux SRT", "把字幕烧进视频", "做最终合成".
This skill should be used to watch a long-running background job (ffmpeg/media encode, qmd or other embedding/vector-DB run, batch agent/LLM pipeline, or a real-browser/agent-browser daemon) until it finishes or wedges, then deliver a verdict (done, needs-attention, or blocked) plus the exact next command, without burning dozens of manual poll commands. Triggers on "babysit this job", "watch this until it's done", "ping me when the encode/embed/batch finishes", "is this background process stuck", "monitor this ffmpeg/qmd run", or any request to wait on a long-running process and be told when it's complete or hung.
Investigate transcription factor binding, cis-regulatory elements, chromatin accessibility, and regulatory variant annotation. Use when asked about TF binding sites, enhancers, promoters, ChIP-seq data, ATAC-seq signals, candidate cis-regulatory elements (cCREs), or the regulatory impact of genomic variants.