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Found 1,718 Skills
Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions. Parses VCF files (streaming, large files), classifies mutation types (missense, nonsense, synonymous, frameshift, splice, intronic, intergenic) and structural variants (deletions, duplications, inversions, translocations), applies VAF/depth/quality/consequence filters, annotates with ClinVar/dbSNP/gnomAD/CADD via ToolUniverse, interprets SV/CNV clinical significance using ClinGen dosage sensitivity scores, computes variant statistics, and generates reports. Solves questions like "What fraction of variants with VAF < 0.3 are missense?", "How many non-reference variants remain after filtering intronic/intergenic?", "What is the pathogenicity of this deletion affecting BRCA1?", or "Which dosage-sensitive genes overlap this CNV?". Use when processing VCF files, annotating variants, filtering by VAF/depth/consequence, classifying mutations, interpreting structural variants, assessing CNV pathogenicity, comparing cohorts, or answering variant analysis questions.
Systematically gather comprehensive travel itinerary requirements through structured discovery questions, MCP-powered research (Perplexity, Exa), and expert detail gathering. Use when users request travel planning, itinerary creation, or trip assistance requiring deep research and personalized requirements gathering. Outputs detailed requirements specification with day-by-day itineraries.
SEO health check for any URL — analyzes meta tags, OG, JSON-LD, sitemap, robots.txt, SERP positions, and scores 0-100. Use when user says "check SEO", "audit this page", "SEO score", "check meta tags", or "SERP position". Do NOT use for generating landing content (use /landing-gen) or social media posts (use /content-gen).
Scaffolds or references a production-ready Node.js REST API with Express 5, TypeScript, Mongoose (MongoDB), Redis, Sentry, JWT auth, bcrypt, rate limiting, and centralized error handling. Use when the user wants to start a new observable and resilient backend, needs a Node.js API boilerplate with security and monitoring, or asks to clone or adapt this template repository.
4-stage funnel that screens all 500+ Hyperliquid perps down to the top trading opportunities. Scores setups 0-400 across smart money, market structure, technicals, and funding. BTC macro filter, hourly trend gate (counter-trend = hard skip), cross-scan momentum tracking. Near-zero LLM tokens — all computation in Python. Use when scanning for new trading opportunities on Hyperliquid, evaluating setups, or checking market conditions.
Automated trailing stop loss for leveraged perpetual positions on Hyperliquid. Monitors price via cron, ratchets profit floors through configurable tiers, and auto-closes positions on breach via mcporter — no agent intervention for the critical path. Works for LONG and SHORT. ROE-based (return on margin) tier triggers that automatically account for leverage. Use when protecting an open Hyperliquid perp position, setting up trailing stops, managing profit tiers, or automating position exits on breach.
Opinionated trailing stop loss preset for Hyperliquid perps with tighter defaults than DSL v4. 4 tiers with per-tier breach counts that tighten as profit grows (3→2→2→1), auto-calculated price floors from entry and leverage, stagnation take-profit that closes if ROE ≥8% but high-water stalls for 1 hour. Same ROE-based engine as DSL v4 — different defaults, fewer knobs. Use when you want aggressive profit protection with minimal configuration.
Production-ready starter project for React + Cloudflare Workers + Hono with core services (D1, KV, R2, Workers AI) and optional advanced features (Clerk Auth, AI Chat, Queues, Vectorize). Complete with planning docs, session handoff protocol, and enable scripts for opt-in features. Use when: starting new full-stack project, creating Cloudflare app, scaffolding web app, AI-powered application, chat interface, RAG application, need complete starter, avoid setup time, production-ready template, full-stack boilerplate, React Cloudflare starter. Prevents: service configuration errors, binding setup mistakes, frontend-backend connection issues, CORS errors, auth integration problems, AI SDK setup confusion, missing planning docs, incomplete project structure, hours of initial setup. Keywords: cloudflare scaffold, full-stack starter, react cloudflare, hono template, production boilerplate, AI SDK integration, workers AI, complete starter project, D1 KV R2 setup, web app template, chat application scaffold, RAG starter, planning docs included, session handoff, tailwind v4 shadcn, typescript starter, vite cloudflare plugin, all services configured
Build buyer and seller agent workflows with Skyfire KYA, PAY, and KYA+PAY tokens. Use when implementing token creation, token introspection and charging, seller service lifecycle, service discovery, Skyfire MCP integration, or enterprise admin operations.
Growth skills for indie Apple developers — user acquisition, analytics interpretation, press/media outreach, community building, and indie business operations. Use when user asks about growing their app, understanding metrics, getting press coverage, or running an indie dev business.
News search, news summarization, news aggregation, hot news, latest news, news organization, news collection. Helps you search for relevant news from the past few days (12-25 articles), generate a beautiful HTML summary page, each news article has a summary and AI in-depth interpretation function, and automatically opens the browser to display it
Analyze media files (PDFs, images, diagrams) that require interpretation beyond raw text. Extracts specific information or summaries from documents, describes visual content. Use for document analysis, image understanding, diagram interpretation, chart analysis, table extraction, and any media requiring visual or contextual interpretation beyond literal text extraction.