Search Results: drug-discovery

Found 26 Skills

Data Processingmims-harvard/tooluniverse

tooluniverse-aging-senescence

Research aging biology, cellular senescence, and longevity using ToolUniverse. Covers senescence markers and pathways, age-related disease genetics, telomere biology, senolytic drug discovery, epigenetic aging clocks, and longevity gene analysis. Integrates GWAS data, gene expression (GTEx age effects), pathway databases, drug repurposing, and literature. Use when asked about aging mechanisms, senescence, senolytics, longevity genes, age-related diseases, or epigenetic clocks.

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Data Processingmims-harvard/tooluniverse

tooluniverse-drug-target-validation

Comprehensive computational validation of drug targets for early-stage drug discovery. Evaluates targets across 10 dimensions (disambiguation, disease association, druggability, chemical matter, clinical precedent, safety, pathway context, validation evidence, structural insights, validation roadmap) using 60+ ToolUniverse tools. Produces a quantitative Target Validation Score (0-100) with GO/NO-GO recommendation. Use when users ask about target validation, druggability assessment, target prioritization, or "is X a good drug target for Y?"

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