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Found 45 Skills
Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
Use when you want to improve response quality through meta-cognitive reasoning. Applies 15+ reasoning methods to reconsider and refine initial outputs.
Litigation Analysis Tool - In-depth Judgment Analysis, Generating Appeal/Retrial Decision Support
Request judgment from random humans when uncertain about subjective decisions. Crowdsourced opinions on tone, style, ethics, and reality checks. CRITICAL - Responses take minutes to hours (or may never arrive).
Generate exactly 5 probability-weighted options for a specific decision point. Forces unconventional alternatives beyond safe defaults. For quick decision-point analysis, NOT full design exploration (use brainstorming for that). Triggers on "대안", "alternatives", "옵션 뽑아", "options", "어떤 방법이", "아이디어", "다른 방법", "선택지".
Complete virtual board of directors — 28 skills covering 10 C-level roles, orchestration, cross-cutting capabilities, and culture frameworks. Features internal quality loop, two-layer memory, board meeting protocol with Phase 2 isolation, proactive triggers, and structured communication standard.
A comprehensive traditional Chinese metaphysics agent ("Yi Jing" expert) that combines Mei Hua Yi Shu (Timing) with Gemini AI for modern interpretation.
Use when analyzing patient records, clinical notes, medical PDFs, FHIR data, or advising on how to present medical data in health-tech products — OCR interpretation, clinical summarization, differential diagnosis support, drug interaction flags
Use for decision-grade Abel causal reads: explain what is driving a market or company node, how two nodes connect, what changes under intervention, or how a real-world choice looks when routed through Abel proxy signals. Use when user says "Abel" or "causal" or "causality" or "drivers" or "what if" in the context of market, business, crypto, or proxy-routed questions.
Run any question, idea, or decision through a council of 5 AI advisors who independently analyze it, peer-review each other anonymously, and synthesize a final verdict. Based on Karpathy's LLM Council methodology. MANDATORY TRIGGERS: 'council this', 'run the council', 'war room this', 'pressure-test this', 'stress-test this', 'debate this'. STRONG TRIGGERS (use when combined with a real decision or tradeoff): 'should I X or Y', 'which option', 'what would you do', 'is this the right move', 'validate this', 'get multiple perspectives', 'I can't decide', 'I'm torn between'. Do NOT trigger on simple yes/no questions, factual lookups, or casual 'should I' without a meaningful tradeoff (e.g. 'should I use markdown' is not a council question). DO trigger when the user presents a genuine decision with stakes, multiple options, and context that suggests they want it pressure-tested from multiple angles.
C-suite orchestration layer that routes founder questions to the right advisor role(s), triggers multi-role board meetings for complex decisions, synthesizes outputs, tracks decisions, and manages cross-functional alignment. Every C-suite interaction starts here. Use when coordinating executive decisions, routing strategic questions, managing board meetings, synthesizing multi-perspective advice, tracking decision history, resolving inter-department conflicts, or when user mentions chief of staff, orchestrator, c-suite coordinator, executive routing, board coordination, decision synthesis, advisor routing, multi-agent coordination, or strategic orchestration.
Meta-cognitive decision support that analyzes current context and surfaces intelligent next-step options to the user. Use this skill when: (1) User explicitly invokes /checkpoint, (2) Significant work has been completed and a checkpoint is valuable, (3) Uncertainty or ambiguity exists about requirements or approach, (4) Task complexity has expanded beyond initial scope, (5) Before finalizing or committing to ensure nothing is missed. This skill pauses execution, assesses the situation holistically, and presents 2-5 contextually-appropriate options via AskUserQuestion, with a recommended option and rationale.