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Found 62 Skills
Calculate statistical significance for A/B tests. Sample size estimation, power analysis, and conversion rate comparisons with confidence intervals.
Strategic planning specialist for task breakdown, dependency management, timeline estimation, and resource allocation. Manual invocation only - expert at decomposing complex projects into manageable tasks, identifying dependencies, assessing risks, and creating actionable roadmaps. Use when starting complex projects, facing overwhelmed scope, needing structured approaches, or requiring systematic task management before implementation.
Master prioritization frameworks, roadmap planning, timeline estimation, and resource allocation. Create executable roadmaps that drive focus and alignment.
Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
Perform statistical modeling and regression analysis on biomedical datasets. Supports linear regression, logistic regression (binary/ordinal/multinomial), mixed-effects models, Cox proportional hazards survival analysis, Kaplan-Meier estimation, and comprehensive model diagnostics. Extracts odds ratios, hazard ratios, confidence intervals, p-values, and effect sizes. Designed to solve BixBench statistical reasoning questions involving clinical/experimental data. Use when asked to fit regression models, compute odds ratios, perform survival analysis, run statistical tests, or interpret model coefficients from provided data.
Estimate fair market rates for creator partnerships based on platform, follower count, engagement rate, niche, and deliverable type. This skill should be used when estimating influencer rates, calculating creator pricing, building a rate card for a campaign, checking if a creator's rate is fair, comparing influencer costs across platforms, budgeting for a creator campaign, evaluating a creator's rate card, figuring out how much to pay an influencer, benchmarking creator rates against market data, or assessing whether a creator is overcharging. For negotiating rates after estimation, see rate-negotiation-playbook. For full creator vetting beyond pricing, see creator-vetting-scorecard.
Apply meta-principles of software craftsmanship: DRY, orthogonality, tracer bullets, and design by contract. Use when the user mentions "best practices", "pragmatic approach", "broken windows", "tracer bullet", or "software craftsmanship". Covers estimation, domain languages, and reversibility. For code-level quality, see clean-code. For refactoring techniques, see refactoring-patterns.
Learn how to manage conversation context in AMCP to avoid LLM API errors from exceeding context windows. This skill covers SmartCompactor strategies, token estimation, configuration, and best practices.
Transform specifications into implementation plans with architecture design and dependency-ordered tasks. Use for spec-to-plan conversion, task breakdown, effort estimation. Skip if no spec exists.
Infrastructure and development cost estimation for technical projects. Use when planning budgets, evaluating build vs buy decisions, or projecting TCO for architecture choices.
Plan a sprint with capacity estimation, story selection, dependency mapping, and risk identification. Use when preparing for sprint planning, estimating team capacity, selecting stories, or balancing sprint scope against velocity.
Codified expertise for demand forecasting, safety stock optimisation, replenishment planning, and promotional lift estimation at multi-location retailers.