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Found 9,229 Skills
Expert in temporal event detection, spatio-temporal clustering (ST-DBSCAN), and photo context understanding. Use for detecting photo events, clustering by time/location, shareability prediction, place recognition, event significance scoring, and life event detection. Activate on 'event detection', 'temporal clustering', 'ST-DBSCAN', 'spatio-temporal', 'shareability prediction', 'place recognition', 'life events', 'photo events', 'temporal diversity'. NOT for individual photo aesthetic quality (use photo-composition-critic), color palette analysis (use color-theory-palette-harmony-expert), face recognition implementation (use photo-content-recognition-curation-expert), or basic EXIF timestamp extraction.
Comprehensive Flutter API reference guide covering widgets, Material Design, Cupertino, animations, gestures, navigation, state management, and platform integration. Use when developing Flutter applications and needing detailed API knowledge for widgets, layout, styling, animations, platform channels, or any Flutter SDK functionality. Essential for building cross-platform mobile, web, and desktop applications with Flutter.
Root cause analysis methods for PHP bugs. Provides 5 Whys technique, fault tree analysis, git bisect guidance, and stack trace parsing.
Implement API versioning with backward compatibility, deprecation notices, and migration paths. Use when managing API versions and backward compatibility. Trigger with phrases like "version the API", "manage API versions", or "handle API versioning".
AI-driven patient-to-trial matching for precision medicine and oncology. Given a patient profile (disease, molecular alterations, stage, prior treatments), discovers and ranks clinical trials from ClinicalTrials.gov using multi-dimensional matching across molecular eligibility, clinical criteria, drug-biomarker alignment, evidence strength, and geographic feasibility. Produces a quantitative Trial Match Score (0-100) per trial with tiered recommendations and a comprehensive markdown report. Use when oncologists, molecular tumor boards, or patients ask about clinical trial options for specific cancer types, biomarker profiles, or post-progression scenarios.
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions. Parses VCF files (streaming, large files), classifies mutation types (missense, nonsense, synonymous, frameshift, splice, intronic, intergenic) and structural variants (deletions, duplications, inversions, translocations), applies VAF/depth/quality/consequence filters, annotates with ClinVar/dbSNP/gnomAD/CADD via ToolUniverse, interprets SV/CNV clinical significance using ClinGen dosage sensitivity scores, computes variant statistics, and generates reports. Solves questions like "What fraction of variants with VAF < 0.3 are missense?", "How many non-reference variants remain after filtering intronic/intergenic?", "What is the pathogenicity of this deletion affecting BRCA1?", or "Which dosage-sensitive genes overlap this CNV?". Use when processing VCF files, annotating variants, filtering by VAF/depth/consequence, classifying mutations, interpreting structural variants, assessing CNV pathogenicity, comparing cohorts, or answering variant analysis questions.
Research historical and cultural background of Bible passages. Use when exploring authorship, original audience, dating, archaeology, geography, political-socio-economic context, social norms, or external historical sources related to Scripture.
Manage Slot teams, billing, credits, and collaborators.
Automatically generate mobile-first responsive CSS/SCSS when creating component styles or mentioning responsive design. Implements standard breakpoints (768px, 1024px), ensures WCAG AA color contrast, creates touch-friendly interfaces (44px minimum targets), adds proper focus indicators, supports reduced motion, scales typography responsively, and provides detailed technical specifications with exact values.
Perform security-focused review of code diffs and pull requests, identifying newly introduced vulnerabilities, security regressions, and unsafe patterns in changed code.
Foundational EVM integration for AAVE-related scripts using viem. Use when user asks to read balances, read/write contracts, send transactions, or set up typed viem clients for Ethereum and Arbitrum.