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Found 413 Skills
Technology adoption and go-to-market strategy based on Geoffrey Moore's "Crossing the Chasm". Use when you need to: (1) identify where your product is in the adoption lifecycle, (2) choose a beachhead market segment, (3) build a "whole product" solution for mainstream buyers, (4) position against incumbent competition, (5) transition from early adopters to mainstream market, (6) develop B2B tech marketing strategy, (7) understand why tech products fail to gain mainstream traction.
Python cheminformatics library for molecular manipulation and analysis. Parse SMILES/SDF/MOL formats, compute descriptors (MW, LogP, TPSA), generate fingerprints (Morgan, MACCS), perform substructure queries with SMARTS, create 2D/3D geometries, calculate similarity, and run chemical reactions.
Implement, review, or improve maps and location features in iOS/macOS apps using MapKit and CoreLocation. Use when working with Map views, annotations, markers, polylines, user location tracking, geocoding, reverse geocoding, search/autocomplete, directions and routes, geofencing, region monitoring, CLLocationUpdate async streams, or location authorization flows. Also use when working with maps, coordinates, addresses, places, directions, distance calculations, or location-based features in Swift apps.
Interactive scientific and statistical data visualization library for Python. Use when creating charts, plots, or visualizations including scatter plots, line charts, bar charts, heatmaps, 3D plots, geographic maps, statistical distributions, financial charts, and dashboards. Supports both quick visualizations (Plotly Express) and fine-grained customization (graph objects). Outputs interactive HTML or static images (PNG, PDF, SVG).
This skill should be used when the user asks to "create a 3D scene", "add a mesh", "implement OrbitControls", "load a GLTF model", "add bloom post-processing", "write a custom shader", "create particle effects", "optimize Three.js performance", "use WebGPU", "add shadows", "animate a model", or mentions Three.js, threejs, WebGL, WebGPU, GLTF, raycaster, shader material, PBR material, or post-processing effects. IMPORTANT: This skill is for VANILLA Three.js (imperative JavaScript). For React Three Fiber (@react-three/fiber, R3F, drei), check the `r3f-best-practices` skill, although three-js skills helps when working with R3F since R3F is a React renderer for Three.js. Provides complete Three.js reference for 3D web graphics including scene setup, geometry, materials, textures, lighting, cameras, loaders, animation, controls, interaction, shaders, post-processing, performance optimization, TSL/node materials, WebGPU, physics, and VR/XR integration.
Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports. Creates comprehensive dataset profiles with metadata, sample information, and download links. Use when users need expression data, omics datasets, or mention ArrayExpress (E-MTAB, E-GEOD) or BioStudies (S-BSST) accessions.
A high-level interactive graphing library for Python. Ideal for web-based visualizations, 3D plots, and complex interactive dashboards. Built on plotly.js, it allows users to zoom, pan, and hover over data points in a browser-based environment. Use for interactive charts, web applications, Jupyter notebooks, 3D data visualization, geographic maps, financial charts, animations, time-series analysis, and building production-ready dashboards with Dash.
Simulate a senior high school Grade 3 liberal arts tutor, using heuristic teaching methods to tutor comprehensive liberal arts problems in politics, history, and geography. Focus on cultivating students' abilities of understanding, memory, and analysis. Applied when students raise liberal arts questions, request explanations of historical events, geographical phenomena, or political principles.
Write, review, and adapt SQL for TiDB with correct handling of TiDB-vs-MySQL differences (VECTOR type + vector indexes/functions, full-text search, AUTO_RANDOM, optimistic/pessimistic transactions, foreign keys, views, DDL limitations, and unsupported MySQL features like procedures/triggers/events/GEOMETRY/SPATIAL). Use when generating SQL that must run on TiDB, migrating MySQL SQL to TiDB, or debugging TiDB SQL compatibility errors.
Legal methods for accessing paywalled and geo-blocked content. Use when researching behind paywalls, accessing academic papers, bypassing geographic restrictions, or finding open access alternatives. Covers Unpaywall, library databases, VPNs, and ethical access strategies for journalists and researchers.
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
Expert implementation of @vis.gl/react-google-maps library for Google Maps in React. Use when building maps, markers, pins, infowindows, places autocomplete, geocoding, draggable markers, polygons, circles, polylines, drawing tools, or any Google Maps JavaScript API integration in React/Next.js applications.