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Found 7,889 Skills
Advanced sub-skill for scikit-learn focused on model interpretability, feature importance, and diagnostic tools. Covers global and local explanations using built-in inspection tools and SHAP/LIME integrations.
Bitrix24 REST API via curl. Use this skill to manage CRM (leads, deals, contacts), tasks, and users.
Build trading systems in the style of Renaissance Technologies, the most successful quantitative hedge fund in history. Emphasizes statistical arbitrage, signal processing, and rigorous scientific methodology. Use when developing alpha research, signal extraction, or systematic trading strategies.
CRITICAL: Use for Robius widget patterns. Triggers on: apply_over, TextOrImage, modal, 可复用, 模态, collapsible, drag drop, reusable widget, widget design, pageflip, 组件设计, 组件模式
Analyze and compare construction bids, proposals, estimates, and subcontractor quotes. Assigns line items to UniFormat II headings, compares absolute cost and cost per unit, produces a leveling spreadsheet (CSV or Excel) and a concise PDF report with scope overlap matrix, contractual term comparison, and a recommendation. Use when the user provides one or more bid documents (PDFs, spreadsheets, or text) to analyze or compare, or asks to "level bids", "compare bids", "bid tabulation", "bid comparison", "bid analysis", or "analyze this bid/quote/proposal" for a construction project.
Migration monitoring, CDC, and observability infrastructure
Эксперт по accessibility дизайну. Используй для WCAG, a11y чеклистов и inclusive design.
Performs initial binary triage by surveying memory layout, strings, imports/exports, and functions to quickly understand what a binary does and identify suspicious behavior. Use when first examining a binary, when user asks to triage/survey/analyze a program, or wants an overview before deeper reverse engineering.
Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring. This skill provides research-backed thresholds from binder design competitions and published benchmarks.
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.