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Found 370 Skills
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
.NET test execution patterns and diagnostics. Use when running tests, analyzing test failures, or configuring test options.
Writing and authoring Quarto documents (.qmd), including code cell options, figure and table captions, cross-references, callout blocks (notes, warnings, tips), citations and bibliography, page layout and columns, Mermaid diagrams, YAML metadata configuration, and Quarto extensions. Also covers converting and migrating R Markdown (.Rmd), bookdown, blogdown, xaringan, and distill projects to Quarto, and creating Quarto websites, books, presentations, and reports.
Configures OrchestKit settings. Use when customizing MCP servers, plugin options, or preferences.
Comprehensive technology-agnostic prompt for analyzing and documenting project folder structures. Auto-detects project types (.NET, Java, React, Angular, Python, Node.js, Flutter), generates detailed blueprints with visualization options, naming conventions, file placement patterns, and extension templates for maintaining consistent code organization across diverse technology stacks.
Guide product managers through creating an Opportunity Solution Tree (OST) by extracting target outcomes from stakeholder requests, generating opportunity options (problems to solve), mapping potentia
Validates JSON data against JSON Schema using the z-schema library. Use when the user needs to validate JSON, check data against a schema, handle validation errors, use custom format validators, work with JSON Schema drafts 04 through 2020-12, set up z-schema in a project, compile schemas with cross-references, resolve remote $ref, configure validation options, or inspect error details. Covers sync/async modes, safe error handling, schema pre-compilation, remote references, TypeScript types, and browser/UMD usage.
Use when making decisions under uncertainty with quantifiable outcomes, comparing risky options (investments, product bets, strategic choices), prioritizing projects by expected return, assessing whether to take a gamble, or when user mentions expected value, EV calculation, risk-adjusted return, probability-weighted outcomes, decision tree, or needs to choose between uncertain alternatives.
Work with Resumx, a Markdown-to-PDF resume renderer. Use when creating, editing, converting, building, styling, or tailoring resumes. Covers syntax, CLI, style options, icons, tags, views, variables, multi-language, page fitting, validation, custom CSS, JSON Resume conversion, and AI-assisted resume writing.
Generate exactly 5 probability-weighted options for a specific decision point. Forces unconventional alternatives beyond safe defaults. For quick decision-point analysis, NOT full design exploration (use brainstorming for that). Triggers on "대안", "alternatives", "옵션 뽑아", "options", "어떤 방법이", "아이디어", "다른 방법", "선택지".
Iterative multi-round deep research with structured analysis frameworks. Use for: deep research on a topic, compare X vs Y, landscape analysis, evaluate options for a decision, deep dive into a technology, comprehensive research with cross-referencing. Triggers: deep research, compare, landscape, evaluate, deep dive, comprehensive research, which is better, should we use.
Think through ideas, investigate problems, and clarify requirements before committing to a change using `/opsx:explore`. Use when the user says "explore an idea", "think through this", "investigate options", or wants to brainstorm before creating a formal change.