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Found 3,962 Skills
Extract table of contents from PDF pages visually and create clickable bookmarks. Use when user wants to add bookmarks/navigation to PDFs based on printed table of contents pages, or needs to convert TOC pages to navigable PDF bookmarks.
Writes or rewrites README.md files tailored to the project type (CLI, library, app, framework, monorepo, or skill bundle). Discovers project context, selects the right structure, writes section by section, and validates against quality checks. Use when creating a README, writing a README from scratch, rewriting a bad README, bootstrapping project documentation, or asking "write a README for this project."
Blender MCP expert for scene inspection, Python scripting, GLTF export, and material/animation extraction. Activate when: (1) using Blender MCP tools (get_scene_info, execute_python, screenshot, etc.), (2) writing Blender Python scripts for extraction or manipulation, (3) exporting scenes to GLTF/GLB for web (Three.js, R3F), (4) debugging material or texture export losses, (5) optimizing GLB files with gltf-transform, (6) using asset integrations (PolyHaven, Sketchfab, Hyper3D Rodin, Hunyuan3D). Covers critical export gotchas, material mapping survival, texture optimization pipeline, headless CLI patterns, and known failure modes.
Comprehensive computational validation of drug targets for early-stage drug discovery. Evaluates targets across 10 dimensions (disambiguation, disease association, druggability, chemical matter, clinical precedent, safety, pathway context, validation evidence, structural insights, validation roadmap) using 60+ ToolUniverse tools. Produces a quantitative Target Validation Score (0-100) with GO/NO-GO recommendation. Use when users ask about target validation, druggability assessment, target prioritization, or "is X a good drug target for Y?"
Perform statistical modeling and regression analysis on biomedical datasets. Supports linear regression, logistic regression (binary/ordinal/multinomial), mixed-effects models, Cox proportional hazards survival analysis, Kaplan-Meier estimation, and comprehensive model diagnostics. Extracts odds ratios, hazard ratios, confidence intervals, p-values, and effect sizes. Designed to solve BixBench statistical reasoning questions involving clinical/experimental data. Use when asked to fit regression models, compute odds ratios, perform survival analysis, run statistical tests, or interpret model coefficients from provided data.
Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions. Parses VCF files (streaming, large files), classifies mutation types (missense, nonsense, synonymous, frameshift, splice, intronic, intergenic) and structural variants (deletions, duplications, inversions, translocations), applies VAF/depth/quality/consequence filters, annotates with ClinVar/dbSNP/gnomAD/CADD via ToolUniverse, interprets SV/CNV clinical significance using ClinGen dosage sensitivity scores, computes variant statistics, and generates reports. Solves questions like "What fraction of variants with VAF < 0.3 are missense?", "How many non-reference variants remain after filtering intronic/intergenic?", "What is the pathogenicity of this deletion affecting BRCA1?", or "Which dosage-sensitive genes overlap this CNV?". Use when processing VCF files, annotating variants, filtering by VAF/depth/consequence, classifying mutations, interpreting structural variants, assessing CNV pathogenicity, comparing cohorts, or answering variant analysis questions.
Expert Next.js performance optimization skill covering Core Web Vitals, image/font optimization, caching strategies, streaming, bundle optimization, and Server Components best practices. Use when optimizing Next.js applications for Core Web Vitals (LCP, INP, CLS), implementing next/image and next/font, configuring caching with unstable_cache and revalidateTag, converting Client Components to Server Components, implementing Suspense streaming, or analyzing and reducing bundle size. Supports Next.js 16 + React 19 patterns.
Titanium SDK official fundamentals and configuration guide. Use when working with, reviewing, analyzing, or examining Titanium projects, Hyperloop native access, app distribution (App Store/Google Play), tiapp.xml configuration, CLI commands, memory management, bridge optimization, CommonJS modules, SQLite transactions, or coding standards. Applies to both Alloy and Classic projects.
Guide for implementing HolmesGPT - an AI agent for troubleshooting cloud-native environments. Use when investigating Kubernetes issues, analyzing alerts from Prometheus/AlertManager/PagerDuty, performing root cause analysis, configuring HolmesGPT installations (CLI/Helm/Docker), setting up AI providers (OpenAI/Anthropic/Azure), creating custom toolsets, or integrating with observability platforms (Grafana, Loki, Tempo, DataDog).
Disaster recovery drill exercises and security checklists for web application projects (SPA, SSR, full-stack web apps). Focused on solo/indie developers using free-tier infrastructure (Vercel, Supabase, Cloudflare, Netlify, Railway, etc.). Bridges big-tech best practices (NIST, Google SRE DiRT, ISO 22301) to indie scale. Use when the user mentions drills, disaster recovery, security audit, incident simulation, project health check, resilience testing, backup strategies, secret rotation, or incident response for web projects. Not for mobile apps, desktop software, CLI tools, or games.
Guide for integrating Agentica SDK with Claude Code CLI proxy
Appwrite Swift SDK skill. Use when building native iOS, macOS, watchOS, or tvOS apps, or server-side Swift applications with Appwrite. Covers client-side auth (email, OAuth), database queries, file uploads, real-time subscriptions with async/await, and server-side admin via API keys for user management, database administration, storage, and functions.