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Found 7,443 Skills
Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases (GWAS Catalog, Open Targets Genetics, ClinVar). Retrieves variant annotations, GWAS trait associations, fine-mapping evidence, locus-to-gene predictions, and clinical significance. Use when asked to interpret a SNP by rsID, find disease associations for a variant, assess clinical significance, or answer questions like "What diseases is rs429358 associated with?" or "Interpret rs7903146".
Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
Transform GWAS signals into actionable drug targets and repurposing opportunities. Performs locus-to-gene mapping, target druggability assessment, existing drug identification, safety profile evaluation, and clinical trial matching. Use when discovering drug targets from GWAS data, finding drug repurposing opportunities from genetic associations, or translating GWAS findings into therapeutic leads.
Manage your agentcash wallet and call any x402-protected API with automatic payment. No API keys, no subscriptions — just a funded wallet (USDC on Base). USE FOR: - Checking wallet balance before API calls - Redeeming invite codes for free credits - Getting deposit address for USDC - Discovering endpoints and pricing on any x402-protected origin - Making paid API requests via the agentcash CLI - Troubleshooting payment failures TRIGGERS: - "balance", "wallet", "funds", "credits" - "redeem", "invite code", "promo code" - "deposit", "add funds", "top up" - "discover", "endpoints", "what APIs", "pricing" - "insufficient balance", "payment failed"
Generates and queries Salesforce metadata with 120-point scoring. Use when creating custom objects, fields, profiles, permission sets, validation rules, or querying org metadata structures via sf CLI.
Titanium Alloy MVC official framework reference. Use when working with, reviewing, analyzing, or examining Alloy models, views, controllers, Backbone.js data binding, TSS styling, widgets, Alloy CLI, sync adapters, migrations, or MVC compilation. Explains how Backbone.js models and collections work in Alloy.
Titanium Alloy CLI and configuration guide. Use when creating, reviewing, analyzing, or examining Alloy projects, running alloy commands (new, generate, compile), configuring alloy.jmk or config.json, debugging compilation errors, creating conditional views, using Backbone.Events for communication, or writing custom XML tags.
Bubble.io plugin development rules, API reference, and coding standards. Use when working on any task in this repo: writing, reviewing, refactoring, or creating initialize.js, update.js, preview.js, header.html, element actions, client-side actions, server-side actions (SSA), Plugin API v4 async/await code, JSDoc, setup files, README, CHANGELOG, marketplace descriptions, or field tooltips. Also use for security audits, code review, debugging, and publishing plugins. Covers instance/properties/context objects, BubbleThing/BubbleList interfaces, data loading suspension, DOM/canvas rules, element vs shared headers, exposed states, event handling, ESLint standards, and Bubble hard limits.
Guide for implementing 1Password secrets management - CLI operations, service accounts, Developer Environments, and Kubernetes integration. Use when retrieving secrets, managing vaults, configuring CI/CD pipelines, integrating with External Secrets Operator, managing Developer Environments, or automating secrets workflows with 1Password.
Work with (B2C/SFCC/Demandware) site archive import archives and metadata XML patterns with the b2c cli. Always reference when using the CLI to work with site archive imports, add custom attributes, create system object extensions, configure site preferences, or understand import/export XML schemas.
Inspect and summarize local Codex/Claude session logs using the ccbox CLI (projects, sessions, history). Use when asked to list discovered projects, find sessions for the current repo/folder, print a session timeline, or produce an evidence-based “what happened” report from a session .jsonl log under CODEX_SESSIONS_DIR.
core usage of pw (playwright cli) on protocol-first surface. use when user requests browser tasks.