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Found 300 Skills
Comprehensive chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, FDA label safety data, DrugBank safety profiles, and STITCH chemical-protein interactions. Performs predictive toxicology (AMES, DILI, LD50, carcinogenicity), organ/system toxicity profiling, chemical-gene-disease relationship mapping, regulatory safety extraction, and environmental hazard assessment. Use when asked about chemical toxicity, drug safety profiling, ADMET properties, environmental health risks, chemical hazard assessment, or toxicogenomic analysis.
Comprehensive epigenomics and gene regulation analysis integrating ENCODE functional genomics data, JASPAR transcription factor binding motifs, SCREEN cis-regulatory elements, ReMap TF binding sites, RegulomeDB variant regulatory scoring, 4D Nucleome chromatin conformation, and Ensembl regulatory features. Performs regulatory element cataloging, transcription factor analysis, variant regulatory impact scoring, chromatin conformation mapping, and gene-centric regulatory landscape profiling. Use when asked about gene regulation, enhancers, promoters, transcription factor binding, epigenetic modifications, chromatin structure, regulatory variants, or non-coding genome function.
Full Sentry SDK setup for Ruby. Use when asked to add Sentry to Ruby, install sentry-ruby, setup Sentry in Rails/Sinatra/Rack, or configure error monitoring, tracing, logging, metrics, profiling, or crons for Ruby applications. Also handles migration from AppSignal or Honeybadger. Supports Rails, Sinatra, Rack, Sidekiq, and Resque.
Use this skill when diagnosing, configuring, or monitoring NICs for AF_XDP / XDP workloads. Covers driver detection, hardware queue configuration, ring buffer sizing, RSS indirection table management, interrupt coalesce tuning, offload control (GSO/GRO/TSO/LRO), VLAN offloads, Flow Director (FDIR) rules with loc pinning and ixgbe wipe bug workaround, RPS/XPS queue CPU mapping, sysctl network tuning, CPU core pinning and NUMA awareness, hardware queue and drop monitoring, softirq and rx_missed_errors analysis, BPF program inspection with bpftool (prog dump xlated, net show), kernel tracing via ftrace and dmesg, perf profiling and flamegraphs, IRQ-to-queue-to-core mapping, bonding interface diagnostics, socket inspection, and a quick diagnostic checklist.
Expert iOS development skill covering SwiftUI, UIKit, Core Data, App Store guidelines, and performance optimization. Use this skill when building, reviewing, or debugging iOS apps - views, navigation, data persistence, animations, or submission preparation. Triggers on SwiftUI layout and state management, UIKit view controller lifecycle, Core Data model design and migrations, App Store Review Guidelines compliance, memory and rendering performance profiling, and Swift concurrency patterns for iOS.
Deterministic 3-phase service health monitoring: Discover, Check, Report. Use when user asks about service status, process health, uptime, or whether services are running. Use for "health check", "is service up", "service status", "what's running", or "check if alive". Do NOT use for HTTP endpoint validation, performance profiling, or log analysis without a specific health concern.
Statistical rule discovery through measurement of Go codebases: Count patterns, derive confidence-scored rules, produce Style Vector fingerprint. Use when analyzing codebase conventions, extracting implicit coding rules, profiling a repo before onboarding or PR automation. Use for "analyze codebase", "find coding patterns", "what conventions does this repo use", "extract rules", or "codebase DNA". Do NOT use for code review, bug fixes, refactoring, or performance optimization.
Constructive critique through 5 HackerNews commenter personas with evidence-based claim validation. Use when user wants devil's advocacy, stress testing, or critical review of ideas, docs, architecture, or code. Use for "roast", "critique this", "poke holes", "devil's advocate", "stress test", or "what's wrong with". Do NOT use for code review (use systematic-code-review), implementation changes, or performance profiling without a specific critique request.
Guides efficient Haskell aligned with GHC practice -- laziness and strictness, purity, fusion, newtypes, pragmas, Core reading, and space-leak avoidance. Use when writing or reviewing Haskell, optimizing or profiling, debugging strictness or memory, or when the user mentions GHC, thunks, foldl vs foldl', list fusion, SPECIALIZE, or UNPACK.
C++ template skill for reading template errors and optimizing compile times. Use when deciphering template error stacks, setting -ftemplate-backtrace-limit, writing concepts and requires-clauses, understanding SFINAE vs concepts, or profiling template instantiation bottlenecks with Templight. Activates on queries about C++ templates, template error messages, concepts, requires expressions, SFINAE, template metaprogramming, or slow template compilation.
Create Docker containers for Huawei Ascend NPU development with proper device mappings and volume mounts. Use when setting up Ascend development environments in Docker, running CANN applications in containers, or creating isolated NPU development workspaces. Supports privileged mode (default), basic mode, and full mode with profiling/logging. Auto-detects available NPU devices.
Use this skill when the user is writing, debugging, profiling, refactoring, reviewing, benchmarking, parallelising, exporting, or explaining JAX code, or when they mention JAX, jax.numpy, jit, grad, value_and_grad, vmap, scan, lax, random keys, pytrees, jax.Array, sharding, Mesh, PartitionSpec, NamedSharding, pmap, shard_map, Pallas, XLA, StableHLO, checkify, profiler, or the JAX repo. It helps turn NumPy or PyTorch-style code into pure functional JAX, fix tracer/control-flow/shape/PRNG bugs, remove recompiles and host-device syncs, choose transforms and sharding strategies, inspect jaxpr/lowering/IR, and benchmark compiled code correctly.