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Found 1,867 Skills
Systematic ACMG/AMP variant classification using ToolUniverse tools. Given a genetic variant (HGVS, rsID, or gene+change), applies all 28 ACMG criteria (PVS1, PS1-4, PM1-6, PP1-5, BA1, BS1-4, BP1-7) through automated database queries and computational predictions. Produces a final 5-tier classification (Pathogenic / Likely Pathogenic / VUS / Likely Benign / Benign) with evidence summary. Use when asked to classify a variant, interpret a VUS, apply ACMG criteria, assess pathogenicity, or determine clinical significance of a germline variant.
Professional, brand-aligned design with structured grids, minimalist layouts, and consistent enterprise patterns.
Convert files between 140+ formats using the ConversionTools MCP server. Use when the user needs to convert documents (Word, PDF, Excel, PowerPoint), data formats (JSON, CSV, XML, YAML, Parquet), images (PNG, JPG, WebP, AVIF, HEIC, JXL, SVG), audio (MP3, WAV, FLAC), video (MOV, MKV, AVI to MP4), e-books (EPUB, MOBI, AZW), OCR text extraction, AI-powered data extraction, AI text-to-speech (TTS), AI speech-to-text transcription (STT), subtitle conversion (SRT, VTT, ASS), or website screenshots.
Use when designing, implementing, or reviewing an embedded accounting engine inside a SaaS, ERP, POS, inventory, payroll, school, clinic, NGO, marketplace, or mobile-money-heavy system. Covers one append-only general ledger, one LedgerPostingService write path, mapping-layer account resolution, IFRS/IFRS for SMEs defaults, subledger tagging, idempotent posting, reversing journals, period locks, audit trails, report projections, and accounting integrity tests.
Codex-native Academic Research Skills suite for deep research, academic paper writing, manuscript review, full research-to-paper pipelines, and experiment planning or validation. Use when the user asks for deep research, literature review, systematic review, meta-analysis, research question refinement, academic paper drafting, paper revision, citation or integrity checks, reviewer simulation, peer review, editorial decision letters, research-to-paper workflows, experiment execution planning, statistical interpretation, or human study protocol support. Also use for Claude-style ARS command aliases such as /ars-plan, ars-plan, /ars-outline, /ars-abstract, /ars-lit-review, /ars-citation-check, /ars-disclosure, /ars-format-convert, /ars-revision-coach, /ars-revision, and /ars-full. This skill vendors ARS role prompts, references, templates, and shared handoff schemas under ars/.
Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or superposition, measure distances or contacts, highlight binding sites or active site residues, color by B-factor/pLDDT, or analyze protein-ligand interactions. Do not use for docking, molecular dynamics, or sequence-only analysis.
Analyze ncu (NVIDIA Nsight Compute) profiling output: SOL% bottleneck classification, roofline analysis, occupancy diagnosis, memory hierarchy analysis, warp stall analysis, metric interpretation, and programmatic .ncu-rep report analysis. NOT for kernel writing or code generation, Nsight Systems (nsys), host-side profiling, or system-level profiling.
Use when reviewing a specific inbound deal before close — when sales has asked for a discount that exceeds AE authority, when the customer has redlined the MSA, when per-deal economics (margin after discount, multi-year payment shape, indemnity exposure) need to be quantified, or when discount approval needs to be routed to a named human approver (Sales Director, VP Sales, CFO, CRO, General Counsel). Covers deal review, discount approval routing, per-deal margin scoring, deal exception handling, MSA redline triage, contract landmine detection (uncapped indemnity, MFN, perpetual license-back, missing DPA), and named-approver chain assembly. NEVER auto-approves — every output is a numeric scorecard plus a routing recommendation to a named human.
Code instrumentation for timing workloads. Two scenarios: (1) Training loop — inject manual timing to report per-iteration latency, throughput (samples/sec), and data load time. (2) Standalone kernel/op — write CUDA event timing code with warmup, per-iteration statistics, and anti-pattern avoidance. Also covers NVTX annotation for labeling profiler timelines. NOT for: running or analyzing profiler tools (nsys, ncu, Nsight Systems, Nsight Compute), writing kernels (Triton, CuTe, CUDA), applying optimizations (CUDA Graphs, gradient checkpointing, fusion), or interpreting roofline/SOL% metrics. Triggers: "measure throughput", "benchmark this function", "time my training loop", "samples per second", "NVTX annotate", "instrument my dataloader", "data load time", "kernel timing", "how do I time".
Implements full disk encryption using Microsoft BitLocker on Windows endpoints to protect data at rest from unauthorized access in case of device loss or theft. Use when deploying encryption for compliance requirements, securing mobile workstations, or implementing data protection controls across the enterprise. Activates for requests involving BitLocker encryption, disk encryption, TPM configuration, or data-at-rest protection.
Comprehensive market environment analysis and reporting tool. Analyzes global markets including US, European, Asian markets, forex, commodities, and economic indicators. Provides risk-on/risk-off assessment, sector analysis, and technical indicator interpretation. Triggers on keywords like market analysis, market environment, global markets, trading environment, market conditions, investment climate, market sentiment, forex analysis, stock market analysis, 相場環境, 市場分析, マーケット状況, 投資環境.
Generate engine-specific test helper libraries for the project's test suite. Reads existing test patterns and produces tests/helpers/ with assertion utilities, factory functions, and mock objects tailored to the project's systems. Reduces boilerplate in new test files.