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Found 305 Skills
This skill is to be used when users request in-depth analysis, thorough thinking, or detailed breakdown of a problem. It is triggered by expressions such as: 'Help me think deeply', 'Please analyze carefully', 'Help me break it down in detail', 'Please organize my thoughts', 'Think carefully', 'Gain in-depth understanding', 'Analyze in detail', or similar phrases indicating a need for systematic thinking. This skill adopts the ReAct-Plan framework: integrating chain-of-thought reasoning with explicit global planning, dynamic prediction, and reflection to overcome short-sighted behaviors.
Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring. This skill provides research-backed thresholds from binder design competitions and published benchmarks.
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.
Debug Node.js/TypeScript/JavaScript applications using the agent-dbg CLI debugger. Use when: (1) investigating runtime bugs by stepping through code, (2) inspecting variable values at specific execution points, (3) setting breakpoints and conditional breakpoints, (4) evaluating expressions in a paused context, (5) hot-patching code without restarting, (6) debugging test failures by attaching to a running process, (7) any task where understanding runtime behavior requires a debugger. Triggers: "debug this", "set a breakpoint", "step through", "inspect variables", "why is this value wrong", "trace execution", "attach debugger", "runtime error".
Perl text processing and scripting with regular expressions. Use for .pl files.
World-class creation of valid, beautiful, and accessible Mermaid diagrams. Use when users request diagrams, flowcharts, sequence diagrams, entity relationship diagrams, state machines, Gantt charts, class diagrams, or any visual representation that can be expressed in Mermaid syntax. Handles all Mermaid diagram types with expert knowledge of syntax, styling, and best practices.
Create a delightful, unexpected "wow" experience for the user by dynamically discovering and creatively combining other enabled skills. Triggers when the user says "surprise me" or any request expressing a desire for an unexpected creative showcase. Also triggers when the user is bored, wants inspiration, or asks for "something interesting".
Mathematical visualization skill for equations, proofs, and geometric concepts. **Triggers when:** - User mentions equations, formulas, or mathematical expressions - Request involves mathematical proofs or derivations - Content includes geometric relationships - User mentions LaTeX, calculus, algebra, geometry, trigonometry - Patterns: "equation", "formula", "prove", "derive", "graph", "plot" **Capabilities:** - LaTeX equation rendering with color-coded components - Function graphing and transformations - Geometric constructions and proofs - 3D mathematical surfaces - Step-by-step derivations with highlights
Vida's thinking framework and expression style. Based on in-depth research on 564 locally archived contents in the repository, 6 core mental models, 9 decision-making heuristics and complete expression DNA are extracted. Purpose: As a thinking consultant, analyze issues of money making, entrepreneurship, asset allocation, information gap, personal IP and geographic arbitrage from Vida's perspective. It is used when users mention "from Vida's perspective", "what would Vida think", "Vida mode", "vida perspective", "perspective of post-00s first-generation rich". It should also be triggered even if the user only says "help me think from Vida's angle", "what would Vida do", "switch to Vida".
Use when resizing images, generating thumbnails, serving responsive images, or optimizing image delivery with Tigris — covers Next.js, Remix, Rails, Django, Laravel, Express
Implements the Syncfusion dotnet Calculate Library for parsing and evaluating formulas using CalcEngine, ICalcData, CalcQuickBase, and ExcelLikeComputations. Supports formula computation, custom functions, cross-sheet references, and XlsIO formula evaluation. Trigger when implementing formula calculations, expression parsing, workbook formula evaluation, or custom function registration.